DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and MAL11

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_011805.3	Gene:	MAL11 / 853207	SGDID:	S000003521	Length:	616	Species:	Saccharomyces cerevisiae

Alignment Length:	454	Identity:	101/454 - (22%)
Similarity:	187/454 - (41%)	Gaps:	85/454 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 TDQGWVASNICL--GGLVGTFLFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFI 115
            |.|..:..|:|:  |.::|..:.|::.:.:|.:..:: .||..|..::.|.:....:.:|....|
Yeast   152 TSQWQIGLNMCVLCGEMIGLQITTYMVEFMGNRYTMI-TALGLLTAYIFILYYCKSLAMIAVGQI 215

  Fly   116 GGAAGGGCFTVIPI-YIAELASDNIRGILGVFLVLTCNFGLVLA-------------FVLGYYFN 166
            ..|...|||..:.: |.:|:....:|..:..:..:...||.:.|             ..|||...
Yeast   216 LSAIPWGCFQSLAVTYASEVCPLALRYYMTSYSNICWLFGQIFASGIMKNSQENLGNSDLGYKLP 280

  Fly   167 YAQVSWIVSSLSFVFVGCFWFMPETPQHLAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQ 231
            :| :.||..:.  :.:|.| |.||:|..|.:.:::.||..||   ..|.|....|...::.|.|:
Yeast   281 FA-LQWIWPAP--LMIGIF-FAPESPWWLVRKDRVAEARKSL---SRILSGKGAEKDIQVDLTLK 338

  Fly   232 KLKTT---EKTTADGVDDDDAATGVTWSDFAEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIF 293
            :::.|   |:..|       :.:|..::.|.....|:..|..|..::.|. .|. .:|.|:...|
Yeast   339 QIELTIEKERLLA-------SKSGSFFNCFKGVNGRRTRLACLTWVAQNS-SGA-VLLGYSTYFF 394

  Fly   294 EQAGSSLPPTVAAIIVGVIQ----LMGTYASTVLVERLGRKILL------------LVSAVGIGL 342
            |:||.:   |..|....:||    |.||..|.|:..|:||..:|            ::..:|.|.
Yeast   395 ERAGMA---TDKAFTFSLIQYCLGLAGTLCSWVISGRVGRWTILTYGLAFQMVCLFIIGGMGFGS 456

  Fly   343 GQSAMGTYSYFQMLGCPVASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILM 407
            |.||.....     |..:|            :.|....|:.::.:.:|:||...::|:..|::..
Yeast   457 GSSASNGAG-----GLLLA------------LSFFYNAGIGAVVYCIVAEIPSAELRTKTIVLAR 504

  Fly   408 STLWLISTCAVKLMPVFTE--------SLGMHGTVFMFASLSFLAAIFIAIFVPETKGKSVDAI 463
            ....|::.....|.|....        ..|::...|...:|:     ::.|.:|||.|::...|
Yeast   505 ICYNLMAVINAILTPYMLNVSDWNWGAKTGLYWGGFTAVTLA-----WVIIDLPETTGRTFSEI 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	96/441 (22%)
MAL11	NP_011805.3	SP	81..563	CDD:273317	100/452 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342467
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830