Protein Alignment CG33281 and VPS73

DIOPT Version :10

• Sequence 1: NP_995620.1
• Gene: CG33281 / 2768938
• FlyBaseID: FBgn0053281
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_011411.3
• Gene: VPS73 / 852774
• SGDID: S000003072
• Length: 486
• Species: Saccharomyces cerevisiae
• Alignment Length: 495
• Identity: 121/495 - (24%)
• Similarity: 215/495 - (43%)
• Gaps: 76/495 - (15%)

  Fly     7 DKYQYLAAISVNIISISYGAF-CGWP-----------SSSFLELSSENSPLDTG----------- 48
            :|::...|:...||..|.|:. .|:.           |.|..::..|..|.|..
Yeast    20 NKHKITKALCYAIIVASIGSIQFGYHLSELNAPQQVLSCSEFDIPMEGYPYDRTWLGKRGYKQCI 84

  Fly    49 PLTPTDQGWVASNICLGGLVGTFLFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIAR 113
            ||.....|.|.|..|:||::|::..|.||:..|||...:.....|::|.:||..:.:...|||.|
Yeast    85 PLNDEQIGIVTSVFCIGGILGSYFATSLANIYGRKFSSLINCTLNIVGSLIIFNSNSYRGLIIGR 149

  Fly   114 FIGGAAGGGCFTVIPIYIAELASDNIRGILGVFLVLTCNFGLVL----AFVLGYYFNYAQV---S 171
            .:.|.:.|....:||::|.|:|.....|:||....:....|::|    |..|...:.:..:   |
Yeast   150 ILVGISCGSLIVIIPLFIKEVAPSGWEGLLGSMTQICIRLGVLLTQGIALPLTDSYRWRWILFGS 214

  Fly   172 WIVSSLSFVFVGCFWF-MPETPQHLAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQK-LK 234
            ::::.|:|.    .|| :.|:|:.|....::.:|:.||...|.:..:.|.:..::.||:::. ..
Yeast   215 FLIAVLNFF----MWFIVDESPKWLLAHGRVTDAKLSLCKLRGVTFDEAAQEIQDWQLQIESGDP 275

  Fly   235 TTEKTTADGVDDDDAATGVTWS---DFAEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQA 296
            ..|.||.:.:...::    .|.   |....|:|....:   |:...|.||..:::.|...|..|
Yeast   276 LIEPTTTNSISGSNS----LWKYLRDRTNVKSRHVITV---LLFGQQFCGINSIVLYGTKIISQ- 332

  Fly   297 GSSLPPTVAAII---VGVIQLMGTYASTVLVERLGRKILLLVSAVGIGLGQSAMGTYSYFQMLGC 358
               |.|..|..|   :.::.::.|...::|:..|.||.||:.|.|.:.:....||.......:..
Yeast   333 ---LYPQHAIRINFFISMVNVLVTILVSLLIHSLPRKPLLMTSTVLVSVTAFIMGIAMNHNKMNL 394

  Fly   359 PVASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEI-MPQKIRSTAIMILMSTL-----WLISTCA 417
            .:. ||::.:..|:       :||..|||:::.|: .||.      |:|....     |:.:...
Yeast   395 LIV-FSFIYMGVFT-------MGLNPLPFIIMREVSKPQD------MVLAQRYGTICNWVGTFII 445

  Fly   418 VKLMPVFTESLGMHGTVF-MFASLSFLAAIFIAIFVPETK 456
            ....|:..:.|.  |.|| :||.::...:.||...|||||
Yeast   446 AYTFPIIHDVLS--GYVFIIFAIIACSISAFIWKKVPETK 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS_GLUT6_8_Class3_like	11..462	CDD:340916	120/491 (24%)
VPS73	NP_011411.3	MFS_GLUT_Class1_2_like	31..484	CDD:340915	119/484 (25%)