DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and MAL31

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_009857.1	Gene:	MAL31 / 852601	SGDID:	S000000502	Length:	614	Species:	Saccharomyces cerevisiae

Alignment Length:	502	Identity:	124/502 - (24%)
Similarity:	201/502 - (40%)	Gaps:	111/502 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ISVNIISISY-----GAFCGWP--SSSFLELSSENSPLDTGPLTPTDQGWVASNICL----GGLV 68
            :|..:|...|     |||...|  ...:..|:|.....:      ....| ...:||    |.:|
Yeast   106 VSTTLIQEGYDTAILGAFYALPVFQKKYGSLNSNTGDYE------ISVSW-QIGLCLCYMAGEIV 163

  Fly    69 GTFLFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGG---GCFTVIPI- 129
            |..:.....|.:|.:..|: |||..|..::.|.:....:.:|.   :|.|..|   |||..:.:
Yeast   164 GLQMTGPSVDYMGNRYTLI-MALFFLAAFIFILYFCKSLGMIA---VGQALCGMPWGCFQCLTVS 224

  Fly   130 YIAELASDNIRGILGVFLVLTCNFGLVLA-------------FVLGYYFNYAQVSWIVSSLSFVF 181
            |.:|:....:|..|..:..|...||.:.|             ..|||...:| :.||....  :.
Yeast   225 YASEICPLALRYYLTTYSNLCWAFGQLFAAGIMKNSQNKYANSELGYKLPFA-LQWIWPLP--LA 286

  Fly   182 VGCFWFMPETPQHLAKINKIEEAEHSLRYYRNIK-SNPAKELSEELQLELQKLKTT---EKTTAD 242
            ||.| |.||:|..|.|..:|::|..||.  |.:. ..|.|||.  :.:||.|:|||   |:..:|
Yeast   287 VGIF-FAPESPWWLVKKGRIDQARRSLE--RTLSGKGPEKELL--VSMELDKIKTTIEKEQKMSD 346

  Fly   243 GVDDDDAATGVTWSDFAEG----KTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPT 303
                    .|..|....:|    :||.|.|..:|..|    ||. :::.|:...:|:||.|   |
Yeast   347 --------EGTYWDCVKDGINRRRTRIACLCWIGQCS----CGA-SLIGYSTYFYEKAGVS---T 395

  Fly   304 VAAIIVGVIQ----LMGTYASTVLVERLGRKIL---------LLVSAVGIGLGQSAMGTYSYFQM 355
            ..|....:||    :..|:.|....:..||..|         ::...:| |||.|  .|:
Yeast   396 DTAFTFSIIQYCLGIAATFISWWASKYCGRFDLYAFGLAFQAIMFFIIG-GLGCS--DTH----- 452

  Fly   356 LGCPVASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKL 420
             |..:.|.:.:.:..|.:.|     |:..:.|.:||||...::|:..|::..:...:|......|
Yeast   453 -GAKMGSGALLMVVAFFYNL-----GIAPVVFCLVSEIPSSRLRTKTIILARNAYNVIQVVVTVL 511

  Fly   421 MPVFTES--------LGMHGTVFMFASLSFLAAIFIAIFVPETKGKS 459
            :.....|        .|.....|..|:|:     :..:.:|||.|::
Yeast   512 IMYQLNSEKWNWGAKSGFFWGGFCLATLA-----WAVVDLPETAGRT 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	111/451 (25%)
MAL31	NP_009857.1	SP	74..557	CDD:273317	124/502 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830