DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and GAL2

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_013182.1	Gene:	GAL2 / 850770	SGDID:	S000004071	Length:	574	Species:	Saccharomyces cerevisiae

Alignment Length:	497	Identity:	124/497 - (24%)
Similarity:	209/497 - (42%)	Gaps:	85/497 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ISVNIISISYGAFC-GWPS---------SSFLELSSENSPLDTGPLTPTDQGWVASNICLGGLVG 69
            :|:..:.:::|.|. ||.:         :.||..........|..|:....|.:.:...:|...|
Yeast    71 VSLLCLCVAFGGFMFGWDTGTISGFVVQTDFLRRFGMKHKDGTHYLSNVRTGLIVAIFNIGCAFG 135

  Fly    70 TFLFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTP--MHLIIARFIGGAAGGGCFTVIPIYIA 132
            ..:.:...|..|||..|..:....::| :||..|...  ....|.|.|.|...||...:.|:.|:
Yeast   136 GIILSKGGDMYGRKKGLSIVVSVYIVG-IIIQIASINKWYQYFIGRIISGLGVGGIAVLCPMLIS 199

  Fly   133 ELASDNIRGILGVFLVLTCNFGLVLAFV-LGYYFNYA------QVSWIVS-----SLSFVFVGCF 185
            |:|..::||.|     ::|...::.|.: |||..||.      .|.|.|.     :.|...:|..
Yeast   200 EIAPKHLRGTL-----VSCYQLMITAGIFLGYCTNYGTKSYSNSVQWRVPLGLCFAWSLFMIGAL 259

  Fly   186 WFMPETPQHLAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAA 250
            ..:||:|::|.::||:|:|:.|:     .|||........:|.||..:..       |::.:..|
Yeast   260 TLVPESPRYLCEVNKVEDAKRSI-----AKSNKVSPEDPAVQAELDLIMA-------GIEAEKLA 312

  Fly   251 TGVTWSDFAEGKTR--KAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQ 313
            ...:|.:....||:  :..|:|:.:..|.||.|......|..|||:..|.. .....:|::||:.
Yeast   313 GNASWGELFSTKTKVFQRLLMGVFVQMFQQLTGNNYFFYYGTVIFKSVGLD-DSFETSIVIGVVN 376

  Fly   314 LMGTYASTVLVERLG-RKILLLVSA-----------VGI------GLGQ-SAMGTYSYFQMLGCP 359
            ...|:.|...||.|| ||.|||.:|           ||:      |..| |:.|..:...:..|
Yeast   377 FASTFFSLWTVENLGHRKCLLLGAATMMACMVIYASVGVTRLYPHGKSQPSSKGAGNCMIVFTC- 440

  Fly   360 VASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVF 424
                         |.:|..|.....:.:::.:|..|.:::|..:.:..::.|:.........|..
Yeast   441 -------------FYIFCYATTWAPVAWVITAESFPLRVKSKCMALASASNWVWGFLIAFFTPFI 492

  Fly   425 TESLGM-HGTVFMFASLSFLAAIF--IAIFVPETKGKSVDAI 463
            |.::.. :|.|||    ..|.|:|  :..|||||||.|::.|
Yeast   493 TSAINFYYGYVFM----GCLVAMFFYVFFFVPETKGLSLEEI 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	107/439 (24%)
GAL2	NP_013182.1	Sugar_tr	74..534	CDD:278511	123/494 (25%)
GAL2	NP_013182.1	MFS	75..518	CDD:119392	114/479 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342497
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.740