DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and HXT10

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_116644.1	Gene:	HXT10 / 850536	SGDID:	S000001883	Length:	546	Species:	Saccharomyces cerevisiae

Alignment Length:	539	Identity:	116/539 - (21%)
Similarity:	201/539 - (37%)	Gaps:	118/539 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LAAISVNIISISYGAFCGWPSSSFLELSSE--NSPLDTGPLTPTDQGWVASNICLGGLVGTFLFT 74
            :.:.||:|:..|..|.........::|:.|  .:.||. |..|....|....:||....|.|:|.
Yeast     1 MVSSSVSILGTSAKASTSLSRKDEIKLTPETREASLDI-PYKPIIAYWTVMGLCLMIAFGGFIFG 64

  Fly    75 W------------------------------------------------------LADRIGRKLC 85
            |                                                      |.|..|||:.
Yeast    65 WDTGTISGFINQTDFKRRFGELQRDGSFQLSDVRTGLIVGIFNIGCALGGLTLGRLGDIYGRKIG 129

  Fly    86 LMWMALPNLLGWVIIPFARTP--MHLIIARFIGGAAGGGCFTVIPIYIAELASDNIRGILGVFLV 148
            ||.:.|..::| ::|..|.:.  ....|.|.:.|...||...:.|..|:|::..::||....|..
Yeast   130 LMCVILVYVVG-IVIQIASSDKWYQYFIGRIVSGMGVGGVAVLSPTLISEISPKHLRGTCVSFYQ 193

  Fly   149 LTCNFGLVLAFVLGY----YFNYAQ--------VSWIVSSLSFVFVGCFWFMPETPQHLAKINKI 201
            |....|:.|.:...|    |.|..|        .:|.:    |:.:|.. .:||:|::|.:..|.
Yeast   194 LMITLGIFLGYCTNYGTKKYSNSIQWRVPLGLCFAWAI----FMVIGMV-MVPESPRYLVEKGKY 253

  Fly   202 EEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDF--AEGKTR 264
            |||..||     .|||........:..|..       |....::.:.|....:|.:.  .:|...
Yeast   254 EEARRSL-----AKSNKVTVTDPGVVFEFD-------TIVANMELERAVGNASWHELFSNKGAIL 306

  Fly   265 KAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGR 329
            ...::|:.:.|..||.||.....|...||...|.. .....:|::|.:....|:.:..:|::.||
Yeast   307 PRVIMGIVIQSLQQLTGCNYFFYYGTTIFNAVGMQ-DSFETSIVLGAVNFASTFVALYIVDKFGR 370

  Fly   330 KILLLVSAVGIGLGQSAMGTYSYFQMLGCPVASFSW--------------VPIAGFSFMLFLAAV 380
            :..||..:..:.:      .:..|..:|   .:..|              |.|....|.:|..|:
Yeast   371 RKCLLWGSASMAI------CFVIFATVG---VTRLWPQGKDQPSSQSAGNVMIVFTCFFIFSFAI 426

  Fly   381 GLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGM-HGTVFMFASLSFLA 444
            ....:.:::|:|..|.::::.|:.|.:...|:.........|..|.|:|. :|.||| ..|.| :
Yeast   427 TWAPIAYVIVAETYPLRVKNRAMAIAVGANWMWGFLIGFFTPFITRSIGFSYGYVFM-GCLIF-S 489

  Fly   445 AIFIAIFVPETKGKSVDAI 463
            ..::..||.||||.:::.:
Yeast   490 YFYVFFFVCETKGLTLEEV 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	100/486 (21%)
HXT10	NP_116644.1	Sugar_tr	52..512	CDD:395036	104/487 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342508
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.830