DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33281 and ERD6

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001031006.1	Gene:	ERD6 / 837414	AraportID:	AT1G08930	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	469	Identity:	129/469 - (27%)
Similarity:	225/469 - (47%)	Gaps:	62/469 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ISISYGAFC-----GWPSSSFLELSSENSPLDTGPLTPTDQGWVASNICLGGLVGTFLFTWLADR 79
            :::| |:||     |:.|.:...::.:.|      |:..:.....|.:.||||:|......:||.
plant    64 VAVS-GSFCTGCGVGFSSGAQAGITKDLS------LSVAEYSMFGSILTLGGLIGAVFSGKVADV 121

  Fly    80 IGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFT-VIPIYIAELASDNIRGIL 143
            :|||..:::.....:.||:.:..|:..|.|...|.:.| .|.|.|: |||:||||:|..::||..
plant   122 LGRKRTMLFCEFFCITGWLCVALAQNAMWLDCGRLLLG-IGVGIFSYVIPVYIAEIAPKHVRGSF 185

  Fly   144 GVFLVLTCNFGLVLAFVLGYYFNYAQVSW----IVSSLSFVF-VGCFWFMPETPQHLAKINKIEE 203
            .....|..|.|:.|.|::|.:     :.|    :|..:..|| |.|.:|:||:|:.|||:.:.:|
plant   186 VFANQLMQNCGISLFFIIGNF-----IPWRLLTVVGLVPCVFHVFCLFFIPESPRWLAKLGRDKE 245

  Fly   204 AEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFAEGKTRKAFL 268
            ...||:..|....:.::|.:               |..|.:|..:.......|:..:.:.....:
plant   246 CRSSLQRLRGSDVDISREAN---------------TIRDTIDMTENGGETKMSELFQRRYAYPLI 295

  Fly   269 IGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGRKILL 333
            ||:||:...||||...:..|.:.:|.:.|  .|..:...::..|.:.....:||||:::||:.||
plant   296 IGVGLMFLQQLCGSSGVTYYASSLFNKGG--FPSAIGTSVIATIMVPKAMLATVLVDKMGRRTLL 358

  Fly   334 LVSAVGIGLGQSAMGTYSYFQMLG-----CPVASFSWVPIAG--FSFMLFLAAVGLLSLPFLVVS 391
            :.|...:||....:.....||..|     .|:  |:.:.:.|  .||     |:|:..||:::::
plant   359 MASCSAMGLSALLLSVSYGFQSFGILPELTPI--FTCIGVLGHIVSF-----AMGMGGLPWIIMA 416

  Fly   392 EIMPQKIRSTAIMILMSTLWL---ISTCAVKLMPVFTESLGMHGTVFMFASLSFLAAIFIAIFVP 453
            ||.|..::.:|..::..|.||   |.|.....|..:..|    |...:|:.:|..:.:||...||
plant   417 EIFPMNVKVSAGTLVTVTNWLFGWIITYTFNFMLEWNAS----GMFLIFSMVSASSIVFIYFLVP 477

  Fly   454 ETKGKSVDAILASL 467
            ||||:|::.|.|.|
plant   478 ETKGRSLEEIQALL 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	112/417 (27%)
ERD6	NP_001031006.1	MFS_GLUT6_8_Class3_like	59..486	CDD:340916	126/462 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930