Protein Alignment CG33281 and SLC2A1

DIOPT Version :9

• Sequence 1: NP_995620.1
• Gene: CG33281 / 2768938
• FlyBaseID: FBgn0053281
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 433
• Identity: 115/433 - (26%)
• Similarity: 182/433 - (42%)
• Gaps: 76/433 - (17%)

  Fly    64 LGGLVGTFLFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMH---LIIARFIGGAAGGGCFT 125
            :||::|:|......:|.||:..::.|.|...:..|::.|::....   ||:.|||.|...|....
Human    74 VGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTG 138

  Fly   126 VIPIYIAELASDNIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSWIVSS-------LSFVFVG 183
            .:|:|:.|::...:||.||....|....|:::|.|.|       :..|:.:       ||.:|:.
Human   139 FVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFG-------LDSIMGNKDLWPLLLSIIFIP 196

  Fly   184 CFW------FMPETPQHLAKINKIEE--AEHSLRYYRNIK--SNPAKELSEELQLELQKLKTTEK 238
            ...      |.||:|:.|. ||:.||  |:..|:..|...  ::..:|:.||.:..:::.|.|
Human   197 ALLQCIVLPFCPESPRFLL-INRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVT-- 258

  Fly   239 TTADGVDDDDAATGVTWSDFAEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPT 303
                           ....|.....|:..||.:.|....||.|..|:..|:..|||:||.. .|.
Human   259 ---------------ILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ-QPV 307

  Fly   304 VAAIIVGVIQLMGTYASTVLVERLGRKILLLVSAVGIGLGQSAMGTYSYFQMLGCPV-------- 360
            .|.|..|::....|..|..:|||.||:.|.|:...|               |.||.:
Human   308 YATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAG---------------MAGCAILMTIALAL 357

  Fly   361 -ASFSWVP----IAGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKL 420
             ....|:.    :|.|.|:.|. .||...:|:.:|:|:..|..|..||.:...:.| .|...|.:
Human   358 LEQLPWMSYLSIVAIFGFVAFF-EVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNW-TSNFIVGM 420

  Fly   421 MPVFTESLGMHGTVFMFASLSFLAAIFIAIFVPETKGKSVDAI 463
            ...:.|.|.......:|..|..|..||....||||||::.|.|
Human   421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEI 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	107/420 (25%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	112/426 (26%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:24847886	282..288		3/5 (60%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144100
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840