Protein Alignment CG33281 and SLC2A9

DIOPT Version :10

• Sequence 1: NP_995620.1
• Gene: CG33281 / 2768938
• FlyBaseID: FBgn0053281
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: XP_011512158.1
• Gene: SLC2A9 / 56606
• HGNCID: 13446
• Length: 615
• Species: Homo sapiens
• Alignment Length: 475
• Identity: 127/475 - (26%)
• Similarity: 197/475 - (41%)
• Gaps: 116/475 - (24%)

  Fly    16 SVNIISISYGAFCGWPSSSFL---ELSSENS-------------------PLDTGPLTPTDQGW- 57
            |:.:.|:: |||    .||||   .||..|:                   |:|...||..   |
Human    55 SLLVASLA-GAF----GSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLL---WS 111

  Fly    58 -VASNICLGGLVGTFLFTWLADRIGRKLCLM---WMALPNLLGWVIIPFARTPMHLIIARFIGGA 118
             ..|...:||||||.:...:...:|||..|:   ..|:...|.......|.....||:.|||.|.
Human   112 VTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 176

  Fly   119 AGGGCFTVIPIYIAELASDNIRGILG----VFLVLTCNFGLVLAF--VLG------YYFNYAQVS 171
            .||...:|:|:|::|::...|||.||    :|:.:....|.:|..  :||      |.|....|.
Human   177 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVP 241

  Fly   172 WIVSSLSFVFVGCFWFMPETPQHLAKINKIEEAEHSLRYYRNI--KSNPAKELSEEL-----QLE 229
            .:|..||..      |:|::|::|. :.|..|| .:::.::..  |::.::|:.|.|     |..
Human   242 AVVQLLSLP------FLPDSPRYLL-LEKHNEA-RAVKAFQTFLGKADVSQEVEEVLAESRVQRS 298

  Fly   230 LQKLKTTEKTTADGVDDDDAATGVTWSDFAEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFE 294
            ::.:...|...|..|........||.:.:                   ||||..|:..||..||.
Human   299 IRLVSVLELLRAPYVRWQVVTVIVTMACY-------------------QLCGLNAIWFYTNSIFG 344

  Fly   295 QAGSSLPPT---VAAIIVGVIQLMGTYASTVLVERLGRKILLLVSAVGIGLGQSAMGTYSYFQML 356
            :||  :||.   ...:..|.|:.:....|.:::|.|||:.||:   .|.||.....||.:....|
Human   345 KAG--IPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLI---GGFGLMGLFFGTLTITLTL 404

  Fly   357 --GCPVASFSWVPIAGFSFMLFLAAVGLLS-----------LPFLVVSEIMPQKIRSTAIMILMS 408
              ..|     |||        :|:.||:|:           :||::..|...|..|..|.:|..:
Human   405 QDHAP-----WVP--------YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGT 456

  Fly   409 TLWLISTCAVKLMPVFTESL 428
            ..|| |..||.|:..|.:.|
Human   457 VNWL-SNFAVGLLFPFIQLL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS_GLUT6_8_Class3_like	11..462	CDD:340916	127/475 (27%)
SLC2A9	XP_011512158.1	MFS_GLUT_Class2	59..466	CDD:340990	122/460 (27%)