DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and slc2a11b

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_005165088.1	Gene:	slc2a11b / 564970	ZFINID:	ZDB-GENE-070705-96	Length:	522	Species:	Danio rerio

Alignment Length:	492	Identity:	114/492 - (23%)
Similarity:	194/492 - (39%)	Gaps:	89/492 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GDKYQYLAAISV---------NIISISYGAFCGWPSSSFLELSSENSPLDTGPLTPTDQGW--VA 59
            |..:||...||:         |.|:.:      |......|:||:...|          .|  :.
Zfish    53 GGTFQYGYNISIINAPTKAVQNFINQT------WTERYSTEISSDMLTL----------LWSIIV 101

  Fly    60 SNICLGGLVGTFLFTWLADRIGRKLCLMWMALPNLLGWVIIPF---ARTPMHLIIARFIGGAAGG 121
            |...:|||||..:...||.|.|||..|::.....||..:.:..   |.|...|:|.||:.|...|
Zfish   102 SIFTIGGLVGASVGGTLAIRFGRKGTLLFNNTFALLAALFMGLSYPASTFELLVIGRFLTGVNAG 166

  Fly   122 GCFTVIPIYIAELASDNIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSWIVSSLSFVFVGCF- 185
            ....|.|:||.|:|...:||.:.:...:....|::...|:|......:..:....||.:.:...
Zfish   167 IAICVQPLYIGEIAPRALRGAMAMGTSIFITGGILTGQVMGLKELLGKDEYWPILLSTICIPAVL 231

  Fly   186 ------WFMPETPQHLAKINKIEE--AEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTAD 242
                  || ||:|::|. |::.::  .:.:|.::..         .::...|::.:: .|:.:|.
Zfish   232 QLLTLPWF-PESPRYLL-IDRGDDIACQKALMWFHG---------QDKYHGEMEDIE-RERVSAL 284

  Fly   243 GVDDDDAATGVTWSDFAEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAG---SSLPPTV 304
            |:....     .|..|.:...|...|..:.:.:..||.|..|:..|...:|.|||   ..:|  .
Zfish   285 GIKPKK-----PWELFTDRSIRWQLLTLVVIHTSQQLNGINAIYFYADYVFTQAGIPDDKIP--Y 342

  Fly   305 AAIIVGVIQLMGTYASTVLVERLGRKILLLVSAVGIGLGQSAMGTYSYFQMLGCPVA-------- 361
            |.:..|..:.:......:|:|.|||:.|::             |.|:...:  |.:.
Zfish   343 ATVGTGACECITALTCGLLIESLGRRALII-------------GGYTLMSV--CCICFTIALTFQ 392

  Fly   362 -SFSWVPIAGFSFML-FLAAVGL--LSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMP 422
             |..|||......:| |:.:.||  ..:..::.:|:..|..|..|.||..|..|........:.|
Zfish   393 DSSPWVPYLSMVCVLAFILSFGLGPGGVTNILTTELFTQTDRPAAYMIGGSINWTSFFVIGMIFP 457

  Fly   423 VFTESLGMHGTVFMFASLSFLAAIFIAIFVPETKGKS 459
            .....|..: ...:|..:..|.|.:|...|||||.|:
Zfish   458 FIVNGLKQY-CFLVFLVICLLVATYIFFVVPETKNKT 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	96/430 (22%)
slc2a11b	XP_005165088.1	Sugar_tr	54..501	CDD:278511	113/491 (23%)
slc2a11b	XP_005165088.1	MFS	98..486	CDD:119392	95/422 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577075
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840