DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and slc2a6

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_689092.6	Gene:	slc2a6 / 560602	ZFINID:	ZDB-GENE-081104-301	Length:	490	Species:	Danio rerio

Alignment Length:	480	Identity:	121/480 - (25%)
Similarity:	210/480 - (43%)	Gaps:	56/480 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 YLAAISVNIISISYGAFCGWPSSSFLELSSENSPLDTGPLTPTDQ-GWVASNICLGGLVGTFLFT 74
            |||..|..:.:.::|....:||....:|...:   ||.......| .|..|...||...|.....
Zfish    25 YLAVFSAVLGNFNFGFALVFPSPVIPQLKQGD---DTRLQMNVHQISWFGSIFTLGAAAGGLSAM 86

  Fly    75 WLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAELASDNI 139
            :|.||:|||:.:|...||::||.:::..|:....|:..||:.|.|||.....||:|::|::..::
Zfish    87 FLNDRVGRKISIMISGLPSVLGLLVMGSAQNFWMLLWGRFLTGIAGGITAGSIPVYVSEISHPSV 151

  Fly   140 RGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSWIVSS------LSFVFVGCFWFMPETPQ-HLAK 197
            ||.||....:|..||.:..:..|....:   .|:..:      :..:.:.|   ||.:|: |:.|
Zfish   152 RGALGSCPQITAVFGSLALYAFGLILPW---RWLAVAGEVPVVIMMLLLCC---MPTSPRYHIMK 210

  Fly   198 INKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFAEGK 262
            .|: .:|..||.:.|...|:...|.:     ::::..||:              ||.|||.....
Zfish   211 GNR-AKAVKSLEWLRGPNSDYMTEFN-----KIERSITTQ--------------GVQWSDLKTKS 255

  Fly   263 TRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERL 327
            ..|..||.:.:....|:.|...:|.|...||.....||.|...|.:||.::|:....:..|:::.
Zfish   256 YYKPILISVVMRFLQQMTGITPILVYLEPIFHLTAISLEPKYDAALVGAVRLISVAIAASLMDKA 320

  Fly   328 GRKILLLVSAVGIGLGQSAMGTYSYFQ-------------------MLGCPVASFSWVPIAGFSF 373
            |||.||..|...|.:...:|..|::..                   ..|......:.:|:.....
Zfish   321 GRKALLFTSGFLIYIAMLSMTMYTHQTPCSQGNLTLTDGLNISSEVQAGAAFDPKTLIPLISAMV 385

  Fly   374 MLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGMHGTVFMFA 438
            ::|..|:|...:.:|::|||:|...|..|..:.:...|:.:....:|......:.|::.....|.
Zfish   386 IIFGYAMGWGPITWLLMSEILPLGARGVASGLCVGVSWITAFVLTQLFMHVVVAYGLYVPFLFFC 450

  Fly   439 SLSFLAAIFIAIFVPETKGKSVDAI 463
            .:|.:..||.|..||||||::::.|
Zfish   451 VVSVVNIIFTAKCVPETKGRTLEEI 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	104/428 (24%)
slc2a6	XP_689092.6	Sugar_tr	27..479	CDD:278511	119/478 (25%)
slc2a6	XP_689092.6	MFS	28..461	CDD:119392	110/461 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577117
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.860