DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and slc2a10

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001104633.1	Gene:	slc2a10 / 560546	ZFINID:	ZDB-GENE-080204-6	Length:	513	Species:	Danio rerio

Alignment Length:	519	Identity:	115/519 - (22%)
Similarity:	213/519 - (41%)	Gaps:	117/519 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LAAISVNII-SISYGAFCGWPSSSFLELSSENSPLDTGPLTPTDQGWVASNICLGGLVGTFLFTW 75
            |..|:|:.: .:.:|...|..|.:..:|.:..|      |....|..|.|.:.:|.|..:.:..|
Zfish     7 LLTITVSTLGGLVFGYELGIISGALPQLQTHFS------LGCVQQEAVVSALLIGSLFASIIGGW 65

  Fly    76 LADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIP----IYIAELAS 136
            |.||.||:..::...|..|.|.||:....:...|:|.|.:.|.|    .||..    |:::|:.:
Zfish    66 LIDRHGRRTSILLSNLLILTGSVILTTGTSFFALVIGRAVIGFA----MTVSSMSCCIFVSEMVT 126

  Fly   137 DNIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQVS-W-------IVSSLSFVFVGCFWFMPETPQ 193
            ...||::.....:....|:::|:.:.|:||..|:: |       |:.||  :.:.....:|:.
Zfish   127 PERRGLMVTLYEVGVTVGILIAYAVNYFFNNVQLTGWRYMFGFAIIPSL--IQLASIVLLPKQ-- 187

  Fly   194 HLAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDF 258
              |::..|.:.:          |..|..|:||.:...|. :.:||            .||  ||.
Zfish   188 --AEVFVIHDDD----------SRQADRLTEETETSNQH-QQSEK------------YGV--SDL 225

  Fly   259 AEGK--TRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAG--SSLPPTVAAIIVGVIQLMGTYA 319
            .:.|  .|:..:||:||:...|..|...:|.|.:.|....|  |:....:|::..|:::::.|..
Zfish   226 FKSKDNMRRRTVIGVGLVLSQQFTGQPNVLFYASTILFSVGFQSNASAILASVGFGIVKVIATLL 290

  Fly   320 STVLVERLGRKILLL--------------------------------------VSA---VGIGLG 343
            :.:..:|.||:.||:                                      :||   .|:|..
Zfish   291 AMLCSDRAGRRSLLIGGCSMLAVGLILTGFLCTQSVIDTTKRCTSVGPHSNLTLSAEHEEGVGFS 355

  Fly   344 QSAMGTYSYFQMLGCPVASFSWVPIAGFSFMLFLAAVGLLSLPF-----LVVSEIMPQKIRSTAI 403
            ...:..:.:.:........:.|:     .|...:|.|...|:.|     :|:|||.|:.||..|.
Zfish   356 SQTLDVHEHLRSFSQSEDIYKWI-----IFTCLMAVVSAFSVSFGPMTWVVLSEIFPKDIRGRAF 415

  Fly   404 MIL----MSTLWLISTCAVKLMPVFTESLGMHGTVFMFASLSFLAAIFIAIFVPETKGKSVDAI 463
            ..:    :.|..:::...:.::.|    :|:.|...|:..:.....:||.:.:|||||||:..|
Zfish   416 SFINCFNVGTNLIVTFSFLSIIDV----IGLSGVFLMYGVVGIAGVVFIYLVLPETKGKSLQDI 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	99/467 (21%)
slc2a10	NP_001104633.1	MFS	10..463	CDD:119392	106/502 (21%)
		Sugar_tr	11..479	CDD:278511	113/515 (22%)
		Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	246..252		2/5 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577047
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940