DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and slc2a1a

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001034897.1	Gene:	slc2a1a / 555778	ZFINID:	ZDB-GENE-030131-3158	Length:	488	Species:	Danio rerio

Alignment Length:	501	Identity:	137/501 - (27%)
Similarity:	214/501 - (42%)	Gaps:	89/501 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 QYLAAISVNII-SISYG-----------AFCGWPSSSFLELSSENSPLDTGPLTPTDQGWVASNI 62
            |.:.|:...:| |:.:|           ...|:.:.::....||..|    |.|.|....|:..|
Zfish    11 QLMMAVGTAVIGSLQFGYNTGVINAPQKIIEGFYNETWHNRYSEYIP----PTTLTTLWSVSVAI 71

  Fly    63 -CLGGLVGTFLFTWLADRIGRKLCLMWMALPNLLGWVIIPF------ARTPMHLIIARFIGGAAG 120
             .:||::|:|......:|.||:..   |.:.|:|.::...|      |.:...|||.|||.|...
Zfish    72 FSVGGILGSFSVGLFVNRFGRRNS---MLIANILAFIAAAFMGFSKLAESWEMLIIGRFIVGLYS 133

  Fly   121 GGCFTVIPIYIAELASDNIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSWIVSS-------LS 178
            |.....:|:|:.|:|..::||.||....|....|:::|.:.|       :..|:.|       |.
Zfish   134 GLSTGFVPMYVGEIAPTSLRGALGTLHQLGIVIGILMAQIFG-------IKEIMGSPTLWPFMLG 191

  Fly   179 FVFV------GCFWFMPETPQHLAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTE 237
            |.|:      ....|.||:|::|. ||:.|||:             ||.:       |:||:.|:
Zfish   192 FTFIPAVLQCALLPFCPESPRYLL-INQNEEAK-------------AKSV-------LKKLRGTD 235

  Fly   238 KTTADGVDDDDAA------TGVTWSD-FAEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQ 295
            ...||..:..|.:      ..||..: |.....|:...|.:.|....|..|..|:..|:..|||:
Zfish   236 DVGADMQEMRDESRQMMREKTVTIPELFRSSLYRQPIFIAIMLQLSQQFSGINAVFYYSTGIFEK 300

  Fly   296 AGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGRKILLLVSAVGIGLGQSAMGTYSYFQMLGCPV 360
            ||.| .|..|.|..|.:....|..|..:|||:||:.|.||..:|:.:....|   :....|...|
Zfish   301 AGVS-EPVYATIGAGAVNTAFTVVSLFIVERVGRRSLHLVGLMGMAVSSVLM---TIAMALLTKV 361

  Fly   361 ASFSWVPI-AGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLW----LISTCAVKL 420
            ...|:|.| |.|||:.|. .:|...:|:.:|:|:..|..|.:|..:...:.|    |:..|.
Zfish   362 EWMSYVSIVAIFSFVAFF-EIGPGPIPWFIVAELFSQGPRPSAFAVAGFSNWFANFLVGMCF--- 422

  Fly   421 MPVFTESLGMHGTVFMFASLSFLAAIFIAIFVPETKGKSVDAILAS 466
              .:.|.|.......:|..|..:..:|....||||||:|.:.|.||
Zfish   423 --QYVEELTGPYVFIIFTVLLLIFFVFTYFKVPETKGRSFEEITAS 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	117/433 (27%)
slc2a1a	NP_001034897.1	Sugar_tr	18..467	CDD:278511	135/494 (27%)
slc2a1a	NP_001034897.1	MFS	62..450	CDD:119392	116/428 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577054
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840