DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and slc2a3a

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_005159482.1	Gene:	slc2a3a / 436916	ZFINID:	ZDB-GENE-040718-390	Length:	575	Species:	Danio rerio

Alignment Length:	525	Identity:	122/525 - (23%)
Similarity:	225/525 - (42%)	Gaps:	98/525 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GDKYQ----YLAAISVNII-SISYGAFCG-----------WPSSSFLELSSENSPLDTGPLTPTD 54
            |:|.|    .|.::|..:| |:.:|...|           :.:::::|...|  |:..|..|..
Zfish     3 GEKKQVTCYLLFSLSTAVIGSLQFGYNTGVINAPEQKLRAFFNATWMERYGE--PISPGVCTIV- 64

  Fly    55 QGW--VASNICLGGLVGTFLFTWLADRIGRKLCLMWMALPNLLGWVIIPFAR--TPMHLIIARFI 115
              |  ..:...:||:.|:|....:|::.||:..::.:.:..|:|..::....  :...:|||..:
Zfish    65 --WSFAVAIFSVGGMAGSFSVGVVANKFGRRKSMILVNVLALIGGGLMGLCTLCSSFEMIIAGRL 127

  Fly   116 GGAAGGGCFT-VIPIYIAELASDNIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQV-----SW-I 173
            ......|.|| :.|:|:.|::...:||..|....|    |:|:..::...|....:     .| |
Zfish   128 MIGLFCGLFTGLTPMYVGEVSPTPLRGAFGTLHQL----GVVVGILIAQIFGLESLLGSDKLWPI 188

  Fly   174 VSSLSFV--FVGCFW--FMPETPQH-LAKINKIEEAEHS---LRYYRNIKSNPAKELSEELQLEL 230
            :.:|:.:  .:.||.  |.||:|:: |..:|:.|:|..:   ||.|.::    .|:: :|::.|.
Zfish   189 LLALTILPAILQCFLLPFCPESPRYLLINLNEEEQARKALVRLRGYEDV----GKDM-QEMKEES 248

  Fly   231 QKLKTTEKTTADGVDDDDAATGVTWSDFAEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQ 295
            .|:...:|.|...:             |.....|:...|.:.|....||.|..|:..|:..||:.
Zfish   249 AKMAMEKKVTIPEL-------------FRSAAYRQPLFIAIMLQLSQQLSGINAVFYYSTGIFKS 300

  Fly   296 AGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGRKILLLVSAVGIGLGQSAMG----------TY 350
            ||.: .|..|.|..||:..:.|..|..||||.||:.|.|:...|:.:...||.          .:
Zfish   301 AGVT-QPIYATIGAGVVNTVFTVVSLFLVERAGRRTLHLIGLGGMAISALAMTIALLLVRFTVCF 364

  Fly   351 SYFQMLGCP--------------------VASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEIMP 395
            ::.::|..|                    :.:..::.||.....:.:..:|...:|:.:|:|:..
Zfish   365 NFVKILNQPQQYLMIMVNVFITFVSKQKDIEALQYLSIAAIFAFVAMFEMGPGPIPWFIVAELFS 429

  Fly   396 QKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGMHGTVFMFASLSFLAAIFIAIF--VPETKGK 458
            |..|..|:.:...:.|..:.......|...|..|.:  ||:...: ||...||..:  ||||||:
Zfish   430 QGPRPAAMAVAGCSNWTANFIVGITFPKLEELCGPY--VFIIFMI-FLIIFFIFTYFKVPETKGR 491

  Fly   459 SVDAI 463
            :.|.|
Zfish   492 TFDEI 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	101/452 (22%)
slc2a3a	XP_005159482.1	Sugar_tr	18..500	CDD:278511	117/510 (23%)
slc2a3a	XP_005159482.1	MFS	66..466	CDD:119392	93/424 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576895
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840