DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33281 and CG14606

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001334690.1	Gene:	CG14606 / 40866	FlyBaseID:	FBgn0037485	Length:	466	Species:	Drosophila melanogaster

Alignment Length:	459	Identity:	159/459 - (34%)
Similarity:	267/459 - (58%)	Gaps:	21/459 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KYQYLAAISVNIISISYGAFCGWPSSSFLELSSENSPLDTGPLTPTDQGWVASNICLGGLVGTFL 72
            ::|::|.::|:|:::::|...||.|.|...|:|:.|||. .|||.|...||.|.|.||.|.|..:
  Fly    17 RWQFIATMTVHIMTLTHGIAVGWLSPSLRLLASDESPLG-DPLTITQASWVGSLIGLGSLTGNII 80

  Fly    73 FTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAELASD 137
            |..|.||:|||:|:.::|:||::.|::|..|:...:|...||:.|.:||||:.|:||:|||:|.:
  Fly    81 FGLLLDRLGRKVCMYFLAIPNMIYWILIYSAQDVTYLYAGRFLAGMSGGGCYVVLPIFIAEIADN 145

  Fly   138 NIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSWIVSSLSFVFVGCFWFMPETPQHLAKINKIE 202
            ::||.|....::..:.|:::.|.|..|..|..:..|:.:|..||:.....:.||||:|.:..:.:
  Fly   146 SVRGALSSMAMMYVSIGMMVGFTLASYLPYYLMPCIIVALPVVFMLSVIGLSETPQYLLRRGRDD 210

  Fly   203 EAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTE---KTTADGVDDDDAATGVTWSDFAEGKTR 264
            :||.|..:|:|: :.|.....|..|.:..|::...   :..:.||.:     .::|.||....|.
  Fly   211 QAEKSFYFYKNL-TPPTSSDKEASQHDAAKIEFDTFRLQVLSGGVTE-----SISWRDFINVPTL 269

  Fly   265 KAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGR 329
            |.|.:...||..|||.|.||:.|||:.||.:.|::|.|..:.|:||..||:|.:::.|||:||||
  Fly   270 KIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNLDPNTSTIVVGAAQLVGIFSAVVLVDRLGR 334

  Fly   330 KILLLVSAVGIGLGQSAMGTYSYFQMLGCPVA-----SFSWVPIAGFSFMLFLAAVGLLSLPFLV 389
            ::|||.|..|:|||:.|:.      :|.|..:     ...|:|:.....:..:|::|:::|.|::
  Fly   335 RVLLLTSMGGMGLGELAIA------LLKCFASDEFLNQNGWLPLVIMCLVACIASLGVIALIFII 393

  Fly   390 VSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGMHGTVFMFASLSFLAAIFIAIFVPE 454
            :.|::|.||||....:.|:|.......|:|:.|......|:..|:||.|.:.....|.:.:|:||
  Fly   394 IIELLPAKIRSIGTSLSMATFSGFIFVALKIYPTMIYDQGLAATMFMSAGMCLFGFIVLGLFLPE 458

  Fly   455 TKGK 458
            ||||
  Fly   459 TKGK 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	137/409 (33%)
CG14606	NP_001334690.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448389
Domainoid	1	1.000	94	1.000	Domainoid score	I384
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0004527
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	9	8.860