DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33281 and slc2a8

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_997963.1	Gene:	slc2a8 / 373140	ZFINID:	ZDB-GENE-030829-25	Length:	498	Species:	Danio rerio

Alignment Length:	483	Identity:	136/483 - (28%)
Similarity:	232/483 - (48%)	Gaps:	57/483 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 YLAAISVNIISISYGAFCGWPSSSFLELSS-ENSPLDTGPLTPTDQGWVASNICLGGLVGTFLFT 74
            ::|..:..:..:|:|...|:.|.:..||.. ::..|.   |:..:..|..|.:.:|..:|..|..
Zfish    37 FIATFAAVLGPLSFGFVLGYSSPAIPELRRIQDLRLQ---LSVEEASWFGSVVTIGAALGGLLGG 98

  Fly    75 WLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAELASDNI 139
            |:.:||||||.||:.|:|.:.|:..|..|:......:.|.:.|.|.|....|:|:||:|:|.:.:
Zfish    99 WIVERIGRKLSLMFCAIPFIFGFTTIIAAQNHWMFYVGRVLTGLASGVTSLVVPLYISEMAHERV 163

  Fly   140 RGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSWIVSSLSF---VFVGCFWFMPETPQHLAKINKI 201
            ||.||..:.|....|::.|:|.|.:.::   .|:..:.|.   :.:....||||||:.|....|.
Zfish   164 RGTLGSCVQLMVVIGIMGAYVTGLFLDW---RWLAVASSIPPTLMLLSMCFMPETPRFLLCQGKR 225

  Fly   202 EEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFAEGKTRKA 266
            .|||.:||:.|. ...||       :.|..:::...|.     ::...:.|    |..:....|.
Zfish   226 REAEDALRFLRG-PDAPA-------EWECARIEDAYKN-----EEQSFSLG----DLKDPGVYKP 273

  Fly   267 FLIGLGLISFNQLCGCFAMLNYTAVIFEQA--GSSLPPTVAAIIVGVIQLMGTYASTVLVERLGR 329
            ..||:.::...|..|..|::.|...|||||  .||   .||.:||...|::.|..:.:::::.||
Zfish   274 LGIGVMMMLLQQFTGINAIMFYAETIFEQAHFKSS---DVATVIVAATQVVFTAIAALIMDKAGR 335

  Fly   330 KILLLVSAVGIGLGQSAMGTYSYFQML-------------------GCPVASFSWVPIAGFSFML 375
            |:||::|.|.:.:.::..|.|....::                   ..|.|..:|:.:....|.:
Zfish   336 KVLLILSGVVMCVSEAVFGVYFKLTVMKPNNSSMTSVLTDTHGLLEDQPSADLAWLAVGSMGFFI 400

  Fly   376 FLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVF---TESLGMHGTVFMF 437
            ...|:|....|:||:|||.|.::|.....:.:.|.|   |||..:...|   .::|...||.:||
Zfish   401 AGFAIGWGPTPWLVMSEIFPTRVRGLGSALCVLTNW---TCAFIVTKTFQNLMDALSSAGTFWMF 462

  Fly   438 ASLSFLAAIFIAIFVPETKGKSVDAILA 465
            ::|.....:|.|.||||||||:::.|.|
Zfish   463 SALCASNVVFTAFFVPETKGKTLEEIQA 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	118/428 (28%)
slc2a8	NP_997963.1	Sugar_tr	39..492	CDD:278511	136/481 (28%)
slc2a8	NP_997963.1	MFS	40..477	CDD:119392	125/465 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576969
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950