DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and CG3285

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	141/457 - (30%)
Similarity:	249/457 - (54%)	Gaps:	20/457 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KYQYLAAISVNIISISYGAFCGWPSSSFLELSSENSPLDTGPLTPTDQGWVASNICLGGLVGTFL 72
            ::|:|..:.:||.:.|:|...||.|....:|.::.||||. |:..:...|:.|.:.:|.::|..:
  Fly    23 RHQFLVTLLLNIATFSHGLGVGWMSPVMRDLQTDESPLDF-PVLVSQVSWIGSLVGIGSVMGNLI 86

  Fly    73 FTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAELASD 137
            ...|.||||||:.|.::|:|....|.:|.|.::...|.|.|.:.|..||.|:.|:|.:|:|:|..
  Fly    87 AGLLMDRIGRKMVLFFIAIPYTTFWCLIYFVQSVEFLYIGRLMAGITGGACYVVLPTFISEIADT 151

  Fly   138 NIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSWIVSSLSFVFVGCFWFMPETPQHLAKINKIE 202
            |:||.||..::|:.|.|::..:::....:|......:..|...:..|.:.:||||.||.:..|.|
  Fly   152 NVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSPPFIIGLPVCYFICNFLIPETPHHLVRKGKFE 216

  Fly   203 EAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFAEGKTRKAF 267
            .|:.|..:|:||:.|..|  :|:...|::.|...|:|        :.|....:.||......||:
  Fly   217 AAKRSFMFYKNIRKNDIK--AEDEFEEMKYLLIKEQT--------EKAKSFDYRDFITRPAFKAY 271

  Fly   268 LIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGRKIL 332
            .....|:..||....|.:..|.|.:|..:.::|...:..||:||:|::|.|.:|:|.::.||:||
  Fly   272 ASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLGMCTIIIGVLQIVGNYVTTLLCDKYGRRIL 336

  Fly   333 LLVSAVGIGLGQSAMGTYSYFQMLGCPVASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEIMPQK 397
            :|.|.:|..:..:|.||:::|.. ...::|..|:|:...|..:||..:||:...|:|:.|:.|.|
  Fly   337 MLTSTLGASVCLTAFGTFTFFAE-AADLSSVDWLPLVILSCFVFLCNIGLVGCLFVVLVELFPAK 400

  Fly   398 IR----STAIMILMSTLWLISTCAVKLMPVFTESLGMHGTVFMFASLSFLAAIFIAIFVPETKGK 458
            ||    ||.::||.||::|    .:|:.|:.....|...|::..:.::|.:.::...|:.||.||
  Fly   401 IRSVSVSTFVVILSSTVFL----TLKIFPICMAVWGTSVTMWSCSGITFFSFLYFCFFLEETNGK 461

  Fly   459 SV 460
            |:
  Fly   462 SL 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	120/405 (30%)
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	132/429 (31%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	127/398 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448388
Domainoid	1	1.000	94	1.000	Domainoid score	I384
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0004527
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	9	8.860