DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and CG15406

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_608761.2	Gene:	CG15406 / 33542	FlyBaseID:	FBgn0031517	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	158/458 - (34%)
Similarity:	257/458 - (56%)	Gaps:	15/458 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 QYLAAISVNIISISYGAFCGWPSSSFLELSSENSPLDTGPLT----PTDQGWVASNICLGGLVGT 70
            |.|.::|..:|:..:|...||.|....:|.   ||.:| ||:    ..:..|:.:.|.:||:.|.
  Fly    18 QLLVSLSATLITFCHGIALGWLSPMLPKLL---SPQET-PLSFYIDVNEASWLGAVISIGGISGN 78

  Fly    71 FLFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAELA 135
            |.|::|.:|.|||:.:..:|:|:...|.:..||::...|.:||...|..|||.|.|:||:|.|:|
  Fly    79 FSFSYLMNRFGRKVSIYALAVPHTCIWFLFYFAQSIEWLYVARVFAGLTGGGMFVVLPIFIGEIA 143

  Fly   136 SDNIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSWIVSSLSFVFVGCFWFMPETPQHLAKINK 200
            .::|||.|..|..||.|.|:::.||:..:..|..:...|..|..::|......||.||.|.:..:
  Fly   144 DNSIRGRLCSFFTLTMNTGIMVGFVVSSHIAYHVIPCAVVGLPVLYVLLATRYPEPPQQLIRWKR 208

  Fly   201 IEEAEHSLRYYRNIKS-NPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFAEGKTR 264
            .||||.||||||.... |.:||.....|....:::...:...:..||:    |::.|||...::.
  Fly   209 EEEAEKSLRYYRRCDGPNVSKEEERAYQKHFDEMRLAIQQQNNDTDDN----GLSMSDFLTKRSL 269

  Fly   265 KAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGR 329
            ||...||.|:..|...|.||..||.:.||:...:.|.|....||:|.:|::||.||..||:|.||
  Fly   270 KALATGLVLMVANIFTGTFAFNNYMSNIFDAVHTQLDPNTNTIIIGAVQILGTLASIYLVDRYGR 334

  Fly   330 KILLLVSAVGIGLGQSAMGTYSYF-QMLGCPVASFS-WVPIAGFSFMLFLAAVGLLSLPFLVVSE 392
            ||||:||..|.|:|.||.|.|::: :.....:::|| |:|:...:|::|:|.||::|:..:|:.|
  Fly   335 KILLIVSCAGSGIGTSAFGLYAFYAEEQKVDLSAFSAWLPVTLMAFIIFIANVGVISVTMVVLVE 399

  Fly   393 IMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGMHGTVFMFASLSFLAAIFIAIFVPETKG 457
            |:|||||:.|....:..|...:..::|..|:....||:..|::..|::|.:...::.:.:.||||
  Fly   400 ILPQKIRAVATSFCLGCLSFFAFASLKTFPLMMFHLGLAATMWFCAAVSVICLFYVVVCLEETKG 464

  Fly   458 KSV 460
            :|:
  Fly   465 RSM 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	140/408 (34%)
CG15406	NP_608761.2	MFS	23..458	CDD:119392	151/442 (34%)
CG15406	NP_608761.2	SP	26..466	CDD:273317	154/447 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448390
Domainoid	1	1.000	94	1.000	Domainoid score	I384
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0004527
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	9	8.860