DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and Slc2a12

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001100921.1	Gene:	Slc2a12 / 308028	RGDID:	1310175	Length:	621	Species:	Rattus norvegicus

Alignment Length:	556	Identity:	126/556 - (22%)
Similarity:	223/556 - (40%)	Gaps:	119/556 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GGDKYQYLAAISVNIISISYGAFCGWPSSSFLELSSENSPLDTGPLTPTDQGWVASNICLGGLVG 69
            |...:.:|.:::..|..:..|...|..|.:.|::.:..:      ||..:|..|.|::.:|..:.
  Rat    39 GPGMFTFLTSVTAAISGLLVGYELGLISGALLQIRTLLA------LTCHEQEMVVSSLLIGAFLA 97

  Fly    70 TFLFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAEL 134
            :.....|.||.||:|.::..:....||.:::..:.:...||..|...|.:.........:||||:
  Rat    98 SLTGGVLIDRYGRRLTIILSSCLLGLGSLVLILSLSYTLLITGRVAIGVSISLSSIATCVYIAEI 162

  Fly   135 ASDNIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSW-----IVSSLSFVFVGCFWFMPETPQH 194
            |..:.||:|.....|....|::.|::..|.|......|     :|..|..:.....:|:|.:|:.
  Rat   163 APQHRRGLLVSLNELMIVTGILFAYISNYAFANISNGWKYMFGLVIPLGVLQAIAMYFLPPSPRF 227

  Fly   195 LAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDF- 258
            |....:.|.|...||..|.|     .:.:|||.|....||             |......|..|
  Rat   228 LVMKGQEEAAGKVLRKLRVI-----SDTAEELTLIKSSLK-------------DEYQYSFWDLFR 274

  Fly   259 AEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAG--SSLPPTVAAIIVGVIQLMGTYAST 321
            ::...|...||||.|:.|.|..|...:|.|.:.:.:..|  |:...::|:..|||::::.|..:|
  Rat   275 SKDNMRTRILIGLTLVFFVQTTGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVVSTIPAT 339

  Fly   322 VLVERLGRKILLLVS------------------------------------------AVG-IGLG 343
            :||:.:|.|..|.:.                                          |.| :.:.
  Rat   340 LLVDHVGSKTFLCIGSSVMAASLLTMGIVNLNINMNFTNICRSHSPLNQSLEELVFYATGNLSVS 404

  Fly   344 QSAMGTY-----SYFQMLGCPV-----------------------------------ASFSWVPI 368
            .|::|.:     .|.:.|..|:                                   |.:.|:.:
  Rat   405 NSSLGEHLKRVTPYSKGLFIPLGNGMEPKGEMAFTSLPNAGLSRTDRQGVTDPAVVPAVYKWLSL 469

  Fly   369 AGFSFMLFLAA--VGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGMH 431
            |  |.::::||  :||..:|:||:|||.|..||..|:.:..|..|.|:..........|:.:|:.
  Rat   470 A--SLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLS 532

  Fly   432 GTVFMFASLSFLAAIFIAIFVPETKGKSVDAILASL 467
            ...|::..:|..:..|:.:|:|||||.|::.|...|
  Rat   533 WVCFIYTVMSLTSLAFVVLFIPETKGCSLEQISMEL 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	110/494 (22%)
Slc2a12	NP_001100921.1	MFS_GLUT12_Class3	46..564	CDD:340993	123/543 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337894
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850