DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33281 and itr1

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_593858.2	Gene:	itr1 / 2543145	PomBaseID:	SPAC4F8.15	Length:	575	Species:	Schizosaccharomyces pombe

Alignment Length:	492	Identity:	118/492 - (23%)
Similarity:	214/492 - (43%)	Gaps:	72/492 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KYQYLAAISVNIISISYGAFCGWPSSSFLELSSENSPLDTGPLTPTDQGWVASNICLGGLVGTFL 72
            |:.::.|.:..|..:.:|...|..|.:.:.:.:.   |....||...:.::.|...||.|:|..:
pombe    85 KWVWVLAFAAGIGGLLFGYDTGVISGALVVIGTS---LGGHELTNGGKEFITSATSLGALLGGII 146

  Fly    73 FTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAELASD 137
            ...|||..|||..:...::..::|.::...|....|:|:.||:.|...|....:||:|::|:|..
pombe   147 AGALADFFGRKPVIAIASIIIIVGSIVQVTAHHLWHMIVGRFVIGWGVGIASLIIPLYLSEIAPS 211

  Fly   138 NIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSW-------IVSSLSFVFVGCFWFMPETPQHL 195
            .|||.|.:..||....|.|:|:.:...|.:....|       :|.:...:|: ..| :||:|:.|
pombe   212 KIRGRLVIIYVLLITAGQVIAYGIDTAFEHVHNGWRWMVGLAMVPAAFQLFI-LIW-LPESPRLL 274

  Fly   196 AKINKIEEAEHSL-RYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFA 259
            .|..:.:||.::| |.|..  ::|            .::||......:||  .|..:|..|....
pombe   275 VKKERSQEAYNTLARIYPT--AHP------------YEIKTKLYLIQEGV--RDPFSGSRWQKIV 323

  Fly   260 EGKTRK----------AFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQL 314
              ||.|          |.::..||.:..||.|..:::.:::.|||..|.: .||...:|:.....
pombe   324 --KTFKELYFNPSNFRALILACGLQAMQQLSGFNSLMYFSSTIFEVVGFN-NPTATGLIIAATNF 385

  Fly   315 MGTYASTVLVERLGRKILLLVSAVGI------------GLGQSAMGTYSYFQMLGCPVASFSWVP 367
            :.|..:..:::..||:||||::..|:            .|.:...|.|:..|       |.:|..
pombe   386 VFTIVAFGVIDFFGRRILLLLTVWGMIAALIVCAVAFHFLPKDENGNYTSGQ-------SNAWAI 443

  Fly   368 IAGFSFMLFLA--AVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWL----ISTCAVKLMPVFTE 426
            :...|.::::|  |.||.:||: ..||:.|..:|.....:..:..|.    |....:.||...|.
pombe   444 VVLISMIVYVASYASGLGNLPW-QQSELFPMSVRGLGTGMSTAVNWAGNLGIGASFLTLMSEITP 507

  Fly   427 SLGMHGTVFMFASLSFLAAIFIAIFVPETKGKSVDAI 463
            :    ||..::..|.||..:......|:....:::.|
pombe   508 T----GTFALYGGLCFLGWLGALFCYPDLTDYTIEEI 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	109/437 (25%)
itr1	NP_593858.2	Sugar_tr	90..544	CDD:278511	117/487 (24%)
itr1	NP_593858.2	MFS	92..529	CDD:119392	114/472 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820