DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and ght6

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_587739.1	Gene:	ght6 / 2538845	PomBaseID:	SPCC1235.13	Length:	535	Species:	Schizosaccharomyces pombe

Alignment Length:	521	Identity:	116/521 - (22%)
Similarity:	201/521 - (38%)	Gaps:	134/521 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VNIISISYGAFCGWPSSSFLELSSENSPLDTG--------------------PLTPT------DQ 55
            :.|:.:.:.:..||...:           |||                    |:|.|      .|
pombe     5 LTIVMLVFVSMAGWMFGA-----------DTGSIGGITNMRDFQSRYADRYDPVTDTYSYSSARQ 58

  Fly    56 GWVASNICLGGLVGTFLFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTP--MHLIIARFIGGA 118
            |.:...:..|..||..|.:.|.||.|::.|:|...|..:.| ||:.....|  :.:::|:...|.
pombe    59 GLLVGMVNTGTTVGCLLSSPLGDRFGKRKCIMGWTLVYITG-VIVQLTTIPSWVQMMVAKIWTGL 122

  Fly   119 AGGGCFTVIPIYIAELASDNIRG----------ILGVFLVLTCNFGLVLAFVLGYYFNYAQVSWI 173
            ..|....:.|.|.:|.:..:|||          .||:|:....|.|      ...|..:.:..|.
pombe   123 GIGALSVIAPGYQSESSPPHIRGAIVTTYQLFITLGIFIAACINMG------THKYTTHPEAQWR 181

  Fly   174 VSSLSFVFVGCFW---------FMPETPQHLAKINKIEE------------AEHSL--RYYRNIK 215
            |.    :.:...|         |:||:|::||...:.||            |:|.:  :.|..|:
pombe   182 VP----IGINLLWGILMFFGMLFLPESPRYLAVKGRNEECMKILTRNAGLPADHPIMQKEYNAIQ 242

  Fly   216 SNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFAEGKTRKAFLIGLGLISFNQLC 280
            ::...||                          |....:|......:.|...|:|:|:::|.||.
pombe   243 ADVEAEL--------------------------AGGPCSWPQIFSNEIRYRTLLGMGVMAFQQLT 281

  Fly   281 GCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGRKILLLVSAVG------ 339
            |......|...:|...|.: .|.:||:|:..:....|:.:..::|..||:..|:|..|.
pombe   282 GNNYFFYYGTQVFRGTGLN-SPFLAALILDAVNFGCTFGAIFVLEYFGRRGPLIVGGVWQSICFF 345

  Fly   340 --IGLGQSAM----GTYSYFQMLGCPVASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEIMPQKI 398
              ..:|..|:    ||.::  ..|..:..||.:.|  |||....|...     :::|.|..|.:.
pombe   346 IYASVGDRALTRPNGTSNH--RAGAVMIVFSCLFI--FSFAQTWAPAA-----YVIVGESYPIRY 401

  Fly   399 RSTAIMILMSTLWLISTCAVKLMPVFTESLGM-HGTVFMFASLSFLAAIFIAIFVPETKGKSVDA 462
            ||....:..::.|..:.......|..:.|:|. :|  ::||:.:..|||.|.:|..||||.:::.
pombe   402 RSKCAAVATASNWFWNFMISFFTPFISNSIGFKYG--YVFAACNLCAAIIIFLFAKETKGLTLEE 464

  Fly   463 I 463
            |
pombe   465 I 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	103/455 (23%)
ght6	NP_587739.1	MFS	10..453	CDD:119392	109/502 (22%)
ght6	NP_587739.1	Sugar_tr	11..469	CDD:278511	115/515 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	2	1.900