DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33281 and Slc2a2

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_037011.2	Gene:	Slc2a2 / 25351	RGDID:	3705	Length:	522	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	127/466 - (27%)
Similarity:	211/466 - (45%)	Gaps:	67/466 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 ELSSENSPLDTGPLTPTDQGW-----------------VASNICLGGLVGTFLFTWLADRIGRKL 84
            :::..::||...|...|...|                 ..|:..:||:|.:|...||.|::||..
  Rat    60 DINGTDTPLIVTPAHTTPDAWEEETEGSAHIVTMLWSLSVSSFAVGGMVASFFGGWLGDKLGRIK 124

  Fly    85 CLMWMALPNLLGWVIIPFAR-TPMH-LIIA-RFIGGAAGGGCFTVIPIYIAELASDNIRGILGVF 146
            .::.....:|.|.:::..:: .|.| |||| |.:.|...|....::|:||.|:|...:||.||..
  Rat   125 AMLAANSLSLTGALLMGCSKFGPAHALIIAGRSVSGLYCGLISGLVPMYIGEIAPTTLRGALGTL 189

  Fly   147 LVLTCNFGLV------LAFVLGYYFNYAQVSW-IVSSLSFV--FVGC--FWFMPETPQHL-AKIN 199
            ..|....|::      |:|:||     .|..| |:..||.|  .:.|  ..|.||:|::| .|:.
  Rat   190 HQLALVTGILISQIAGLSFILG-----NQDYWHILLGLSAVPALLQCLLLLFCPESPRYLYLKLE 249

  Fly   200 KIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFAEGKTR 264
            :...|:.||:..|..: :..|::: |::.|.::..|.:|.:...:             |.:...|
  Rat   250 EEVRAKKSLKRLRGTE-DVTKDIN-EMRKEKEEASTEQKVSVIQL-------------FTDPNYR 299

  Fly   265 KAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGR 329
            :..::.|.|....|..|...:..|:..||:.||.| .|..|.|.||.|.::.|..|.:|||:.||
  Rat   300 QPIVVALMLHLAQQFSGINGIFYYSTSIFQTAGIS-QPVYATIGVGAINMIFTAVSVLLVEKAGR 363

  Fly   330 KILLLVSAVGIGLGQSAMGTYSYFQMLGCPVA-SFSWVP----IAGFSFMLFLAAVGLLSLPFLV 389
            :.|.|...:|       |...:.|..||..:. .|:|:.    .|.|.|:.|. .:|...:|:.:
  Rat   364 RTLFLAGMIG-------MFFCAVFMSLGLVLLDKFTWMSYVSMTAIFLFVSFF-EIGPGPIPWFM 420

  Fly   390 VSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGMHGTVFMFASLSFLAAIFIAIFVPE 454
            |:|...|..|.||:.:...:.|:.:...........:.||.: ..|:||.:..:..:|....|||
  Rat   421 VAEFFSQGPRPTALALAAFSNWVCNFIIALCFQYIADFLGPY-VFFLFAGVVLIFTLFTFFKVPE 484

  Fly   455 TKGKSVDAILA 465
            |||||.|.|.|
  Rat   485 TKGKSFDEIAA 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	113/438 (26%)
Slc2a2	NP_037011.2	MFS_GLUT_Class1	12..488	CDD:340989	121/457 (26%)
Slc2a2	NP_037011.2	Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	312..318		2/5 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337866
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850