DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33281 and Slc2a6

DIOPT Version :10

Sequence 1:NP_995620.1 Gene:CG33281 / 2768938 FlyBaseID:FBgn0053281 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_766247.2 Gene:Slc2a6 / 227659 MGIID:2443286 Length:497 Species:Mus musculus


Alignment Length:474 Identity:122/474 - (25%)
Similarity:213/474 - (44%) Gaps:44/474 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 YLAAISVNIISISYGAFCGWPSSSFLELSSENSP---LDTGPLTPTDQGWVASNICLGGLVGTFL 72
            :||..:..:.:.|:|....:.|....||...:.|   ||     .....|..|...||...|...
Mouse    38 FLATFAAVLGNFSFGYALVYTSPVIPELKLSSDPALHLD-----KIQASWFGSVFTLGAAAGGLS 97

  Fly    73 FTWLADRIGRKLCLMWMALPNLLGWVIIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAELASD 137
            ...|.|.:||||.:|:.|:|:.:|:.|:..||....|::.|.:.|.|||.....||:|::|:|..
Mouse    98 AMLLNDLLGRKLSIMFSAVPSAIGYAIMAGARGLWMLLLGRMLTGFAGGLTAACIPVYVSEIAPP 162

  Fly   138 NIRGILGVFLVLTCNFGLVLAFVLGYYFNYAQVSWIVSSLSFVFVGCFWFMPETPQHLAKINKIE 202
            ::||.||....|...||.:..:.||....:..::........:.:....|||.:|:.|...::.|
Mouse   163 DVRGALGATPQLMAVFGSLSLYALGLLLPWRWLAVAGEGPVLIMILLLSFMPNSPRFLLSKSRDE 227

  Fly   203 EAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSDFAEGKTRKAF 267
            ||..:|.:.|         ...|:..|.::::...:.         .::.|:|::..|.:..:..
Mouse   228 EALQALTWLR---------ADSEVHWEFEQIQDNVRR---------QSSRVSWAEAREPRVYRPV 274

  Fly   268 LIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGRKIL 332
            ||.:.:....||.|...:|.|...||:.....||....|.|||.::|:....:.|.::..|||:|
Mouse   275 LIAVLMRFLQQLTGITPILVYLQTIFDNTSVVLPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVL 339

  Fly   333 LLVSAVGIGLGQSAMGTYSYFQMLGCPVASFSWVPI-----AGFSF---------MLFLA--AVG 381
            |.|||..:......:|.  |.|.:..|:...|.|.|     ..|::         |||:.  |:|
Mouse   340 LYVSASVMFAANLTLGL--YVQFVPRPLTPNSTVEIVTLGDTAFNYLTLIPLLATMLFIMGYAMG 402

  Fly   382 LLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGMHGTVFMFASLSFLAAI 446
            ...:.:|::||::|.:.|..|..:.:...||.:........:...:.|:....|.|:::..|:.:
Mouse   403 WGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTNYFLLAVNAFGLQVPFFFFSAICLLSLL 467

  Fly   447 FIAIFVPETKGKSVDAILA 465
            |....||||:|:|::.|.|
Mouse   468 FTGCCVPETRGRSLEQIEA 486

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33281NP_995620.1 MFS_GLUT6_8_Class3_like 11..462 CDD:340916 120/469 (26%)
Slc2a6NP_766247.2 Dileucine internalization motif. /evidence=ECO:0000255 5..6
MFS 38..483 CDD:475125 120/469 (26%)
Blue background indicates that the domain is not in the aligned region.

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