Protein Alignment CG33298 and DRS2

DIOPT Version :9

• Sequence 1: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: NP_009376.2
• Gene: DRS2 / 851207
• SGDID: S000000024
• Length: 1355
• Species: Saccharomyces cerevisiae
• Alignment Length: 1411
• Identity: 417/1411 - (29%)
• Similarity: 647/1411 - (45%)
• Gaps: 314/1411 - (22%)

  Fly   137 TDSPPGSAAPAGRGHSRVGSKTDFILPPGH----------KEEPAREPSAPTSATGGRGHSRQAS 191
            |.|..||.:.....|:...     .:||.|          .::...|.....:......|..|.|
Yeast    28 TTSHSGSRSKVTNSHANAN-----YIPPSHVLPEETIDLDADDDNIENDVHENLFMSNNHDDQTS 87

  Fly   192 RSESIY--------TLRRTEAPPWWKR--------LTLCNYNTGDKFEERSYRTVVPNHTVPPKT 240
            .:.:.:        :||..:.|..:.|        .|.......:.||...|..|..|.......
Yeast    88 WNANRFDSDAYQPQSLRAVKPPGLFARFGNGLKNAFTFKRKKGPESFEMNHYNAVTNNELDDNYL 152

  Fly   241 PKRD--------------------HPNGQ----------------FVGNKIRTTKYTLLSFIPKN 269
            ..|:                    ..||:                :..|.|.||||...:|:||.
Yeast   153 DSRNKFNIKILFNRYILRKNVGDAEGNGEPRVIHINDSLANSSFGYSDNHISTTKYNFATFLPKF 217

  Fly   270 LLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNT 334
            |.::|.:.|||:|:....:..||.:|...:...:..:|.||.|:|:|:..||.:|..|||.:||:
Yeast   218 LFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNS 282

  Fly   335 TCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKR 399
            |..::....:.:.:.:|.::|||||:.:.:.|.:|||.::|.:|:|:|:|||:|.:||||||||.
Yeast   283 TAEIFSEAHDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLKI 347

  Fly   400 REVVRGFEEMQSIFVPSKFV---------SRVEADAPTTKLYRFHGALIHPTGERVPISTECLLL 455
            :         ||....:||:         .:|.::.|.:.||.:.|.:. ....::|:|.:.::|
Yeast   348 K---------QSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYEGTMT-LNDRQIPLSPDQMIL 402

  Fly   456 RESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIG-C 519
            |.:.|:||.:|.|:|::.|||||.:.|.:....||:.||:.:|..:|....:|::|.::.:|| .
Yeast   403 RGATLRNTAWIFGLVIFTGHETKLLRNATATPIKRTAVEKIINRQIIALFTVLIVLILISSIGNV 467

  Fly   520 RMWLSSFTHFPVPYLP-PNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNV 583
            .|..:...|....||. .||.....:....||   ::...::|:||:||:||.|..|.|.|.:::
Yeast   468 IMSTADAKHLSYLYLEGTNKAGLFFKDFLTFW---ILFSNLVPISLFVTVELIKYYQAFMIGSDL 529

  Fly   584 DLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYS 648
            ||:..:|:..|..|..::.||||||::||:|||||||.|.|.|:.|.:.|..|      ::|
Yeast   530 DLYYEKTDTPTVVRTSSLVEELGQIEYIFSDKTGTLTRNIMEFKSCSIAGHCY------IDK--- 585

  Fly   649 KPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGII 713
                     ||.|.    .|.:..|                      :.||.....|:
Yeast   586 ---------IPEDK----TATVEDG----------------------IEVGYRKFDDL------- 608

  Fly   714 EVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSP 778
                             ::||              |.|
Yeast   609 -----------------KKKL--------------NDP--------------------------- 615

  Fly   779 PPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSI 843
                                         |:.:||                     :||..:|.:
Yeast   616 -----------------------------SDEDSP---------------------IINDFLTLL 630

  Fly   844 ATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVS 908
            ||.        ...:|..:       :||...|:|.||||.|||..........:.|.||.:.|.
Yeast   631 ATC--------HTVIPEFQ-------SDGSIKYQAASPDEGALVQGGADLGYKFIIRKPNSVTVL 680

  Fly   909 MPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILR 973
            :...|..:||::|.:..|:|:||.||.:.| .....|.|:.||||:.|:..|...::...|..:|
Yeast   681 LEETGEEKEYQLLNICEFNSTRKRMSAIFR-FPDGSIKLFCKGADTVILERLDDEANQYVEATMR 744

  Fly   974 EQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLL 1038
            .     |:.||.||||.|.:|.|.::..:|.:|.:.:.|...:|:||..:|.::...:|.||.|:
Yeast   745 H-----LEDYASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILI 804

  Fly  1039 GATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAA 1103
            |||.|||:|||||||||.:|..|||.:||||||:.||||||..|.:|.::.|.|:.:...:||..
Yeast   805 GATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLIINEETRDDT 869

  Fly  1104 E-------TAINFYLTDMENDKTT---STLGYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFL 1158
            |       .|:|      |:..:|   :||           |||:|||:|.|.|:|:.:..|  |
Yeast   870 ERNLLEKINALN------EHQLSTHDMNTL-----------ALVIDGKSLGFALEPELEDYL--L 915

  Fly  1159 RLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAV 1223
            .::|.|.:|:|||.:|||||.:||:||.:.:...||||||||||||||.|.|||||||.|||||.
Yeast   916 TVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAA 980

  Fly  1224 MAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMY 1288
            .:||..:.:|::|::|||.||.|.|.|:|..|||.||||.|.....|||.....||||.:|:...
Yeast   981 RSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWT 1045

  Fly  1289 LMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFF 1353
            :..|||.||..||..|||:|:.|:..||.:.|.|||.|:.|..:..:.||..:::..:.|.::|.
Yeast  1046 MSFYNLFFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFI 1110

  Fly  1354 VALCAYAESDVGI-----------WEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSF 1407
            ..:..|.   .|.           |.:|.|:..:.:...|...|:....||...:::|..||..:
Yeast  1111 GTILIYR---YGFALNMHGELADHWSWGVTVYTTSVIIVLGKAALVTNQWTKFTLIAIPGSLLFW 1172

  Fly  1408 YLFAIVYDSVCMNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVL 1453
            .:|..:|.|:..:....|..|.|:...:.|.|.||.:::..:.|::
Yeast  1173 LIFFPIYASIFPHANISREYYGVVKHTYGSGVFWLTLIVLPIFALV 1218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	PhoLip_ATPase_N	249..299	CDD:292826	18/65 (28%)
		ATPase-Plipid	250..1473	CDD:273734	392/1236 (32%)
		E1-E2_ATPase	302..>394	CDD:278548	35/91 (38%)
		Cation_ATPase	<880..965	CDD:289987	30/84 (36%)
		HAD_like	<1177..1240	CDD:304363	37/62 (60%)
		PhoLip_ATPase_C	1223..1468	CDD:292829	76/242 (31%)
DRS2	NP_009376.2	ATPase-Plipid	198..1240	CDD:273734	392/1236 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820