DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33298 and AT1G26130

DIOPT Version :9

Sequence 1:	NP_995666.1	Gene:	CG33298 / 2768929	FlyBaseID:	FBgn0032120	Length:	1517	Species:	Drosophila melanogaster
Sequence 2:	NP_001185096.1	Gene:	AT1G26130 / 839154	AraportID:	AT1G26130	Length:	1185	Species:	Arabidopsis thaliana

Alignment Length:	1415	Identity:	431/1415 - (30%)
Similarity:	643/1415 - (45%)	Gaps:	330/1415 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 SATGGRGHSRQASRSESIYTLRRTEA---PPWWK-------RLTLCNYNTGDKFEERSYRTVVPN 233
            :...||...|:...|: ::||...:|   |...|       |:..||.....:.|.|:|
plant     2 ATVSGRRRKRKIQLSK-LFTLTGAKACFKPDHSKIGRSGFSRVVFCNQPDSPEAESRNY------ 59

  Fly   234 HTVPPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFG 298
                             ..|.:|||||||.:|:||:|.|||.||||.||:.:.:|::.| ::.:.
plant    60 -----------------CDNYVRTTKYTLATFLPKSLFEQFRRVANFYFLVVGILSFTP-LAPYT 106

  Fly   299 KEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLS 363
            ...|::|:.||:..|..|:..||.||:..|..:||...||:.| ...:...:|:.||||||:.:.
plant   107 AVSAIVPLTFVILATMFKEGVEDWRRKQQDIEVNNRKVRVHRG-NGNFDLREWKTLRVGDILKVE 170

  Fly   364 NNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRR---EVVRGFEEMQSIFVPSKFVSRVEAD 425
            .||..|||::||.:|....|||::|.:||||||||.:   ||.....|..:.   ..|.:.::.:
plant   171 KNEFFPADLVLLSSSYEDAVCYVETMNLDGETNLKLKQGLEVTLSLREELNF---RDFEAFIKCE 232

  Fly   426 APTTKLYRFHGALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKR 490
            .|...||.|.|.: ...||:.|:|.:.||||.|:|:|||||.|:|::.|.:||.:.|::.|..||
plant   233 DPNANLYSFVGTM-DLKGEKYPLSPQQLLLRGSKLRNTDYIYGVVIFTGPDTKVVQNSTDPPSKR 296

  Fly   491 SQVEQQMNIDVIWCVIILLILCVVGAIGCRMWL-SSFTHFPVP--YLPPNKLT-------ANMES 545
            |.:|::|:..:....:::..|...|::...:|. ..|.:..:.  ||.|:..:       |.|.:
plant   297 SMIERKMDKIIYLMFLMVFSLAFFGSVLFGIWTRDDFQNGVMERWYLKPDDSSIFFDPKRAPMAA 361

  Fly   546 MWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQH 610
            ::.|.|.:::....||:||||:||:.|:||...|:.::.::..|.:|....|..|:.|||||:..
plant   362 IYHFLTALMLNSYFIPISLYVSIEIVKVLQSIFINQDIHMYYEEADKPAHARTSNLNEELGQVGT 426

  Fly   611 IFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSK----------------PGAPAPPLIP 659
            |.:|||||||.|.|.|.:|.:.|:.|....:|:|....|                ....|.|.:.
plant   427 ILSDKTGTLTCNSMEFIKCSIAGTAYGRGVTEVEMAMDKRKGSALVNQSNGNSTEDAVAAEPAVK 491

  Fly   660 NDNLNSDMAQLTQGTYLT-PHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPA 723
            ..|...:  ::..|.::| .||..||:|..:||:|:|||
plant   492 GFNFRDE--RIMDGNWVTETHADVIQKFFQLLAVCHTVI-------------------------- 528

  Fly   724 NLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPA 788
                                           |:|
plant   529 -------------------------------PEV------------------------------- 531

  Fly   789 QSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQG 853

plant   532 ----------------------------------------------------------------- 531

  Fly   854 KRMKLPSSKTGTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVS----MPMAGA 914
                  ...||.|        .||||||||.|.|.||.........|:...|.|.    :.....
plant   532 ------DEDTGKI--------SYEAESPDEAAFVIAARELGFEFFTRTQTTISVRELDLVTGERV 582

  Fly   915 TREYEILKVLPFDSSRKCMSIVVR-QIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILRE-QTQ 977
            .|.|.:|.||.|.||:|.||::|: |.|  :::|..|||||.:...|      |..|...| :|:
plant   583 ERLYSVLNVLEFSSSKKRMSVIVQDQDG--KLLLLCKGADSVMFERL------SESGRKYEKETR 639

  Fly   978 QLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLE-NRERRLRDSFAKLESNLTLLGAT 1041
            ..::.||..|||.|::|.|.|:..:|..:..|..|.:.|:. :||..:.:...|:|.||.|||||
plant   640 DHVNEYADAGLRTLILAYRELDENEYEVFTERISEAKNSVSADREALIDEVTEKIEKNLVLLGAT 704

  Fly  1042 GIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARS------- 1099
            .:||:||:|||:.|..|..|||.:|||||||.||||||.::..|..:.|:.|.:...:
plant   705 AVEDKLQNGVPDCINKLAQAGIKIWVLTGDKMETAINIGFACSLLRRDMKQIIINLETPEIQQLE 769

  Fly  1100 ----RDAAETAINFYLTDMENDKTTSTLGYGQ----SLRKKQRALVVDGKTLTFILDPKSKLILP 1156
                :||...|:.      ||.....|.|..|    ....|..||::|||:|.:.|:...|.|
plant   770 KSGEKDAIAAALK------ENVLHQITSGKAQLKASGGNAKAFALIIDGKSLAYALEEDMKGI-- 826

  Fly  1157 FLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQ 1221
            ||.|:..||||:||||:|.|||.:.::||......|||||||||||.|:|.||:||||||.||||
plant   827 FLELAIGCASVICCRSSPKQKALVTRLVKTGSGQTTLAIGDGANDVGMLQEADIGVGISGVEGMQ 891

  Fly  1222 AVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQ 1286
            |||::|..:.:|||||||||.||:|||.|:|:||.||||||..|.|.:|.|:.|..||.....:.
plant   892 AVMSSDIAIAQFRYLERLLLVHGHWCYRRISKMICYFFYKNITFGFTLFLYEAYTSFSATPAYND 956

  Fly  1287 MYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALY----Q 1347
            .||.||::.|||||.:.:|::|:.|:....||.|.||:.|...:.:.    |..:|..::    .
plant   957 WYLSLYSVFFTSLPVICLGIFDQDVSAPFCLKFPVLYQEGVQNLLFS----WRRILSWMFHGFCS 1017

  Fly  1348 SLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSF----- 1407
            :::|||  ||..:.........|.|.....|...:..|.:    |.|  .|.:||::..|
plant  1018 AIIIFF--LCKTSLESQAFNHEGKTAGRDILGGTMYTCVV----WVV--SLQMVLTISYFTLIQH 1074

  Fly  1408 ----------YLFAIVYDSVCMNCFGVRSS---YWVIFVCFASA-VHWLVIMLSTVVAVLPRLLL 1458
                      |||.:||.|:     .:|.|   |.|.....|.| .:|:..:...:..::|..:.
plant  1075 VVVWGSVVIWYLFLMVYGSL-----PIRMSTDAYMVFLEALAPAPSYWITTLFVVLSTMMPYFIF 1134

  Fly  1459 TTVRISLCPDDSTKVILQSKRERSRGEALLVTWSRSTSASSIYRITDYGS 1508
            :.:::...|             .|.|...|:.:....|.|..:.:...||
plant  1135 SAIQMRFFP-------------MSHGTVQLLRYEDQCSNSGNFEMGRQGS 1171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	PhoLip_ATPase_N	249..299	CDD:292826	23/49 (47%)
		ATPase-Plipid	250..1473	CDD:273734	409/1297 (32%)
		E1-E2_ATPase	302..>394	CDD:278548	37/91 (41%)
		Cation_ATPase	<880..965	CDD:289987	32/89 (36%)
		HAD_like	<1177..1240	CDD:304363	39/62 (63%)
		PhoLip_ATPase_C	1223..1468	CDD:292829	83/267 (31%)
AT1G26130	NP_001185096.1	PhoLip_ATPase_N	43..106	CDD:292826	28/86 (33%)
		ATPase-Plipid	59..1150	CDD:273734	412/1334 (31%)
		Cation_ATPase	523..628	CDD:289987	45/279 (16%)
		COG4087	<842..900	CDD:226572	36/57 (63%)
		PhoLip_ATPase_C	893..1144	CDD:292829	84/280 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830