Protein Alignment CG33298 and atp9b

DIOPT Version :10

• Sequence 1: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: XP_005170114.1
• Gene: atp9b / 568160
• ZFINID: ZDB-GENE-060503-583
• Length: 1136
• Species: Danio rerio
• Alignment Length: 1300
• Identity: 337/1300 - (25%)
• Similarity: 580/1300 - (44%)
• Gaps: 278/1300 - (21%)

  Fly   208 WKRLTL----CNYNTGDKFEERSYRTVVPNHTVPPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPK 268
            ||.|..    |..:|..:.:|...|||...|   |:..:..:|.     |.|:..||.:::|:|.
Zfish    79 WKVLCSSCCECLVHTCRRKKELKARTVWLGH---PEKCEEKYPK-----NAIKNQKYNIVTFVPG 135

  Fly   269 NLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINN 333
            .|.:||....||||:.:....:||.:..........|:.|||.||.|::..::.||...||.:|:
Zfish   136 VLYQQFKFFLNLYFLVVACSQFVPSLKIGYLYTYWAPLGFVLAVTMVREAVDEVRRCRRDKEMNS 200

  Fly   334 TTCRVYDGETERYK-KVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNL 397
               ::|...|.|.| :||..:::|||::.:..|:.:|||::.||||:..|.|:|.|..|||||:.
Zfish   201 ---QLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIPADMIFLRTSEKTGSCFIRTDQLDGETDW 262

  Fly   398 KRREVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHGALIH-----PTGERVPISTECLLLRE 457
            |.|..|...:.:.::.......:.|....|...::.|.|....     |..|.:.|..   .|..
Zfish   263 KLRIGVACTQRLPALGDLFSISAYVYVQKPQLDIHSFEGNFTREDCDPPIHESLSIEN---TLWA 324

  Fly   458 SRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMN-----IDVIWCVIILLILCVVGAI 517
            |.:..:..:.|:|:|.|.|.:|::|.|..:.|...::.::|     :.:...|:.::::.:.|.:
Zfish   325 STVVASGTVIGVVIYTGKEMRSVMNTSQSKNKVGLLDLELNRLTKALFLAQVVLSVVMVALQGFL 389

  Fly   518 GCRMWLSSFTHFPVPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNN 582
            |  .|..:...|                       :|:...:||:||.|.:::.|....:.|..:
Zfish   390 G--PWFRNLFRF-----------------------VVLFSYIIPISLRVNLDMGKSAYGWMIMKD 429

  Fly   583 VDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIY 647
                  |....|..|...|.||||::.::.||||||||:|:|:|:|.
Zfish   430 ------ENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMVFKRL------------------ 470

  Fly   648 SKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGI 712
                                                                             
Zfish   471 ----------------------------------------------------------------- 470

  Fly   713 IEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPS 777
                .:|                          |:..|..|..::.|.....|.:::.
Zfish   471 ----HLG--------------------------TVSYGTDTMDEIQSHIIQSYAQVSS------- 498

  Fly   778 PPPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITS 842
                      |||:       .|||.|:|:.:.:.|:|.:: ||:|:.|....:|.|:.:    :
Zfish   499 ----------AQSN-------GSSASSTPSRKPQPPAPKVR-KSVSSRIHEAVKAIALCH----N 541

  Fly   843 IATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILV 907
            :.....::..|...:..|::....:  :|....|:|.||||:|||....|....|:||....:.:
Zfish   542 VTPVYESRVNGANAEPESTEADQDF--SDDNRTYQASSPDEVALVRWTESVGLTLVNRDLTSLQL 604

  Fly   908 SMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGIL 972
            ..| ||....|.||::.||.|..|.|.|:||:..:.:|..|.||||.::..::   .:|.   .|
Zfish   605 KTP-AGQILTYYILQIFPFTSESKRMGIIVREEATGDITFYMKGADVAMASIV---QYND---WL 662

  Fly   973 REQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTL 1037
            .|:...:    ||||||.||:||::|....|.|:..|:.:.::|:.:|..::......||..:.|
Zfish   663 EEECGNM----AREGLRTLVVAKKSLTEEQYQDFENRYNQAKLSIHDRNLKVAAVVESLEREMEL 723

  Fly  1038 LGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMEL-IRLTARSRD 1101
            |..||:||:||..|..|:..|.:|||.:|:|||||.|||..||.|:.|.::..:: :.....:|.
Zfish   724 LCLTGVEDQLQADVRPTLELLRNAGIKIWMLTGDKLETATCIAKSSHLVSRNQDIHVFKPVSNRG 788

  Fly  1102 AAETAINFYLTDMENDKTTSTLGYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCAS 1166
            .|...:|.:                  .||...|||:.|.:|...|.....   .|:.|:.:|.:
Zfish   789 EAHLELNAF------------------RRKHDCALVISGDSLEVCLRYYEH---EFVELACQCPA 832

  Fly  1167 VLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLP 1231
            |:|||.:|.|||.:|:::::....||.|||||.|||||||.||.|:||.|:||.||.:||||::.
Zfish   833 VVCCRCSPTQKAQIVRLLQQHTANRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSIT 897

  Fly  1232 RFRYLERLLLAHGYWCYDRLSRMILYFFYK-------NAAF--VFLIFWYQLYCGFSGQVMMDQM 1287
            :|:::.|||:.||...|.|.:.:..:..::       .|.|  :|......||.||
Zfish   898 QFKHIGRLLMVHGRNSYKRSAALGQFVMHRGMIISTMQAVFSSIFYFASVPLYQGF--------- 953

  Fly  1288 YLML-YNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKN---GRLGVAYRPHDFWLILLDALYQS 1348
             ||: |..|:|..|..:: |.|:.|..::.|..|.|||:   || .::::....|:::  ::||.
Zfish   954 -LMVGYATIYTMFPVFSL-VLDQDVKPEMALLYPELYKDLTKGR-SLSFKTFLIWVLI--SIYQG 1013

  Fly  1349 LVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIV 1413
            .::.:.||..:.:..|.:.....|   :.:...|:..|:.||:|..|.|::.::|| :.||.::.
Zfish  1014 GILMYGALVLFDQEFVHVVAISFT---ALILTELLMVALTIRTWHWLMVVAQLISL-ACYLASLA 1074

  Fly  1414 YDSVCMN-CFGV----RSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKV 1473
            :    :| .||:    ..::..:.........|.|.:: |:|:.||..::..::....|...:|:
Zfish  1075 F----LNEYFGIGRVTLGAFLDLSFITTRVFLWKVCVI-TLVSCLPLYIIKYLKRKFSPPSYSKL 1134

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	299/1127 (27%)
atp9b	XP_005170114.1	P-type_ATPase_APLT_Neo1-like	119..1045	CDD:319841	303/1160 (26%)
		Cation_ATPase	565..649	CDD:463817	32/86 (37%)