Protein Alignment CG33298 and atp8b3

DIOPT Version :10

• Sequence 1: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: XP_003201102.3
• Gene: atp8b3 / 566530
• ZFINID: ZDB-GENE-050208-424
• Length: 1174
• Species: Danio rerio
• Alignment Length: 1307
• Identity: 392/1307 - (29%)
• Similarity: 605/1307 - (46%)
• Gaps: 266/1307 - (20%)

  Fly   248 GQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGV 312
            |::..|.:|:.|||.|:|.|.||.|||.|.|||:|:.||:|..||.|:.......|:|:|.||.|
Zfish    56 GRYADNVVRSYKYTPLTFFPLNLYEQFQRAANLFFLLIVILQCVPVIATIPWYTTMLPLLIVLFV 120

  Fly   313 TAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRT 377
            ...|||..|..||.||.:||...|.:.  ..|.:|.|||:::.||||:.:..::.:|||:|||.:
Zfish   121 RGCKDLATDVGRRRSDAQINRRPCDIL--TPEGFKTVKWKDVCVGDILRVHKDQVIPADLLLLCS 183

  Fly   378 SDPQGVCYIDTCDLDGETNLKRREV-------VRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFH 435
            ::|..:||::|.|:|||||||.|:.       :.|....|::   :.|.:.|..:.|...|:.|.
Zfish   184 TEPYSLCYVETADIDGETNLKFRQALTVTHTELNGDSTEQNL---AAFDAIVRCEEPNGNLHSFR 245

  Fly   436 GALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNID 500
            |. .|..|||..:.|:.||||.:.|:||||..|:.:|.|.::|.:.|....:.|::.||..:|..
Zfish   246 GE-FHWKGERHLLGTDHLLLRGTVLRNTDYAYGLTIYTGSDSKILQNCGRLKLKKTHVEILLNKT 309

  Fly   501 VIWCVIILLILCVVGAIGCRMWLSSFT-HFPVPYLPPNKLTANMESMWIFWTYIVILQVMIPLSL 564
            |:..::.:|...::.|||..::....: ::.|..:.....:...:....||.||::|...:|:||
Zfish   310 VLVILLFMLTTALLLAIGAGIFEYRISPNYDVVSIVQRDSSPAYQGFLTFWGYIILLSPSMPMSL 374

  Fly   565 YVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRC 629
            |:|.|:..::....|..:|:::..:||.....|...:.|||||:.|:.:|||||||:|:::||:|
Zfish   375 YITFEVIHMVHCLLIGWDVEMYWEDTNCPAHARTTTLNEELGQVGHLLSDKTGTLTQNRLLFRQC 439

  Fly   630 VVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRI----------- 683
            .:.|..|.....:     |||            |:....:.:.|. |....||:
Zfish   440 FIAGHIYGDISQK-----SKP------------LDLSWNRFSCGG-LKFSDQRLVDKLRGRGSLE 486

  Fly   684 -QEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTI 747
             |||...||:|:||:
Zfish   487 CQEFFTALALCHTVM-------------------------------------------------- 501

  Fly   748 INGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSESES 812
                                                                        ||.:
Zfish   502 ------------------------------------------------------------SEWK- 505

  Fly   813 PSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYE 877
                                                                      ||.|.|:
Zfish   506 ----------------------------------------------------------DGLPHYQ 512

  Fly   878 AESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGS 942
            |.||||.|||.||.......|:|:.:.:.:|  ..|.||.|::|.:|.|.|.|:.||::||..|.
Zfish   513 AASPDEEALVCAARELGWVFLSRTRDTLTIS--EMGLTRNYQLLALLDFTSKRRRMSVLVRSPGG 575

  Fly   943 QEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWW 1007
            | :.||:||||..|:..|      ..:..|:|.|.:.|:.:|:..||.|.:|.|.:..|.:|:|.
Zfish   576 Q-LKLYSKGADIVILERL------QKDWPLQESTDRALELFAQSCLRTLCVAVRPVPEALWTEWS 633

  Fly  1008 ARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDK 1072
            ........:..|:|..|.:.:.::|.:|.|||.|.||||||:|||||||||..||:.||||||||
Zfish   634 RALNLAGTATGNQETLLEEIYDQMEKDLMLLGVTAIEDRLQEGVPETIASLRRAGVKVWVLTGDK 698

  Fly  1073 PETAINIAYSAKLF---------TQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTLGYGQS 1128
            .|||:|:.|:.||.         .:..:|:...:.:.|........::||
Zfish   699 TETAVNVGYACKLMDPDTTLIQGEELRQLLESPSPNVDVKSKEPEVWITD--------------- 748

  Fly  1129 LRKK----QRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELN 1189
              ||    :.|||:.|..|. .|...|:....|:.||.:|.||||||.||.|||.:|::|::...
Zfish   749 --KKAVMSKAALVISGPELA-ELTKSSEWGAKFVALSGQCQSVLCCRVTPAQKAEVVEMVRKHSA 810

  Fly  1190 LRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRM 1254
            ..|:|||||||||:||:.|.:|||:.|.||.|||:.|||.|.:|.:|.:|||.||:|.|.|:|.:
Zfish   811 SITMAIGDGANDVNMIKTAHIGVGLCGVEGSQAVLNADFALAQFSFLRKLLLVHGHWSYYRISIL 875

  Fly  1255 ILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKN 1319
            :.||.||..||..:..||..|.|||.|.|.:..|:.|:...:||||....|::::.::....|..
Zfish   876 LRYFLYKTTAFALVHTWYSFYNGFSAQPMYESWYISLFTTTYTSLPIQCTGIFEQDISARSCLCW 940

  Fly  1320 PYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVH 1384
            |.:|..|:....:.|......||.:.|.|::.|||.:.....|.:.......||..|.|||..:.
Zfish   941 PEIYSIGQKKQLFNPSVLASTLLYSFYSSIIFFFVPMGILQYSALDFQTLAITIETSVLFATTLE 1005

  Fly  1385 CAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRSSYWVIFV---CFASAVHWLVIML 1446
            ..:..:.||..:|.:::.||.:|:|..:...|..:.....: .|:.:..   .:::...||.|.:
Zfish  1006 VILCTKYWTKWNVAAVIFSLAAFFLSTLALHSTRLFTASPK-DYFFLGASQNAYSTPEVWLTIFV 1069

  Fly  1447 STVVAVLPRLLLTTVRISLCPDDSTKVILQSKRERSRGEAL-LVTW-SRST-SASSIYRITDYGS 1508
            :|.|||||.:....:.:.|...:..|:      ..|..|.: |.:| .|.| ...|.|.::....
Zfish  1070 TTCVAVLPSITTRALGVVLANPNKHKI------HSSANEPVELQSWFQRGTVQRRSSYAVSQGKG 1128

  Fly  1509 KNQIITT 1515
            ..::|||
Zfish  1129 FGKLITT 1135

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	352/1135 (31%)
atp8b3	XP_003201102.3	None