Protein Alignment CG33298 and atp8b2

DIOPT Version :9

• Sequence 1: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: XP_021322579.1
• Gene: atp8b2 / 323754
• ZFINID: ZDB-GENE-030131-2474
• Length: 1359
• Species: Danio rerio
• Alignment Length: 1345
• Identity: 419/1345 - (31%)
• Similarity: 653/1345 - (48%)
• Gaps: 287/1345 - (21%)

  Fly   249 QFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVT 313
            |:..|.|.|:||.:::|:|.||.|||..|||.||:|:::|..:|:||:......::|::.||.:|
Zfish    60 QYASNCIMTSKYNIITFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLSIT 124

  Fly   314 AVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTS 378
            ||||..:|..|..||.::||...:|..|..  .:|.||..:|||||:.|.||:.|.||:|||.:|
Zfish   125 AVKDATDDYFRHKSDNQVNNRQSQVLIGGI--LQKEKWMNVRVGDIIKLENNQFVAADLLLLSSS 187

  Fly   379 DPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHGALIHPTG 443
            :|.|:|||:|.:||||||:|.|:.:....|:......::|...|..:.|..||.||.|.| :...
Zfish   188 EPHGLCYIETAELDGETNMKVRQSLSVTSELGDPNNLAQFDGEVVCEPPNNKLDRFCGTL-YWRE 251

  Fly   444 ERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIIL 508
            .:.|:|.:.:|||...|:||:...|:|::||.:||.|.|:...::||:.:::.||..|:|....|
Zfish   252 CKYPLSNQNMLLRGCVLRNTESCYGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFL 316

  Fly   509 LILCVVGAIGCRMWLSS----FTHFPVPYLPP--NKLTANMESMWIFWTYIVILQVMIPLSLYVT 567
            :.:.|:.|||..:|...    |..| :|:.||  |.|.:...|   ||:|::||..::|:||||:
Zfish   317 VCMGVILAIGNAVWEKEVGALFQSF-LPWDPPVDNFLFSAFLS---FWSYVIILNTVVPISLYVS 377

  Fly   568 IELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVN 632
            :|:.::...:.|:.:..:|.:.:|...|.|...:.|||||:::||:|||||||:|.|.|.:|.:|
Zfish   378 VEVIRLGHSYFINWDRRMFCSRSNTAAEARTTTLNEELGQVEYIFSDKTGTLTQNIMTFNKCSIN 442

  Fly   633 GSDY----NHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAIC 693
            |..|    |...::.:::.....:...||........|.:.|.......|   .:.||..||::|
Zfish   443 GHAYGEVVNILAAQQKRVQPLDFSSWNPLADRGFCFYDQSLLEAVMVGDP---AVHEFFRVLSLC 504

  Fly   694 NTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVV 758
            :||:
Zfish   505 HTVM------------------------------------------------------------- 508

  Fly   759 SIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLS 823
                                                             ||.:|
Zfish   509 -------------------------------------------------SEEKS----------- 513

  Fly   824 NSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYEAESPDELALVN 888
                                                           :|..:|:|:||||.|||.
Zfish   514 -----------------------------------------------EGELVYKAQSPDEGALVT 531

  Fly   889 AAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGAD 953
            ||.::.....:|:|..|  :....|....|.:|.:|.|::.||.||::||. ....|.||.||||
Zfish   532 AARNFGFVFRSRTPGTI--TTQELGKAVTYTLLAILDFNNIRKRMSVIVRN-PEGRIRLYCKGAD 593

  Fly   954 SSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLE 1018
            :.::..|..|:|.     :...|...|:.||.:|||.|.:|.|.|:...:.:|..|.:..:.:.:
Zfish   594 TVLLERLHSCNHE-----VMTITSDHLNEYAVDGLRTLAVAYRDLSEEQWDEWSERFRGADKATD 653

  Fly  1019 NRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSA 1083
            .||.||..::.::|.::.|||||.|||:||:|||||||.|..|.|.:|||||||.|||:||.||.
Zfish   654 CREDRLAAAYEEIEQDMMLLGATAIEDKLQEGVPETIAILSLANIKIWVLTGDKQETAVNIGYSC 718

  Fly  1084 KLFTQQM----------------------ELIRLTARSRD-----------------------AA 1103
            |:.|..|                      |.:..:||:||                       ||
Zfish   719 KMLTDDMTEVFIVNGHTVQSVREELRKARERMLESARTRDGGKEAEAQGWSGACAFGNGCGAGAA 783

  Fly  1104 ETAINFYLTDMENDKTTSTLGYGQSLRKK---QRALVVDGKTLTFILDPKSKLILPFLRLSKRCA 1165
            ..|.|:   ..:..|.........||.:.   :.||::.|.:|...|:  :.:...||..:..|.
Zfish   784 AAAANW---APDESKCPPAQAPPSSLLESISGEFALIISGHSLAHALE--ADMEREFLETACACR 843

  Fly  1166 SVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTL 1230
            :|:|||.||||||.:|::||......||||||||||||||:.|.:|||||||||:|||:|:|::.
Zfish   844 AVICCRVTPLQKALVVELVKRHKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSF 908

  Fly  1231 PRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLI 1295
            .:||:|:||||.||.|.|.|:.|.:.||||||.||..:.||:..:||||.|.:.||.::.|||::
Zfish   909 SQFRFLQRLLLVHGRWSYLRMCRFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIV 973

  Fly  1296 FTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFV--ALCA 1358
            :||||.||:|::|:.|.|...|:.|.||:.|:|.:.:...:|::.:...:|.|:|:||:  ::.:
Zfish   974 YTSLPVLAMGIFDQDVPEQRSLEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVVLFFIPYSVLS 1038

  Fly  1359 YAESDVGI-----WEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVC 1418
            :|....|:     ..|..|...:.:....|..|::...||.::...:..|||::  |.|:
Zfish  1039 HATQSNGVPLADYQTFAVTTATALVIVVSVQIALDTGYWTAINHFFVWGSLGTY--FTIL----- 1096

  Fly  1419 MNCFGVRSSYWVIFVCFASAVH--------------WLVIMLSTVVAVLPRLLLTTVRISLCPDD 1469
               |.:.||  ::|..|....|              ||.|.|:||:.:.|.|....:::.|.|..
Zfish  1097 ---FAMHSS--ILFSIFPKQFHFLGSAHNTLGQPVVWLTIALATVICIAPVLAFRFLKLDLKPQL 1156

  Fly  1470 S-----TKVILQSKRERSRGEALLVTWSRSTSASSIYRITDYGSK 1509
            |     |:::||.||:.....|..|..:.:...|.:.|:...||:
Zfish  1157 SDTVRYTQLVLQKKRKPGGRAARGVGSTGAAGGSGLGRLGRGGSR 1201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	PhoLip_ATPase_N	249..299	CDD:292826	23/49 (47%)
		ATPase-Plipid	250..1473	CDD:273734	408/1306 (31%)
		E1-E2_ATPase	302..>394	CDD:278548	42/91 (46%)
		Cation_ATPase	<880..965	CDD:289987	32/84 (38%)
		HAD_like	<1177..1240	CDD:304363	38/62 (61%)
		PhoLip_ATPase_C	1223..1468	CDD:292829	86/265 (32%)
atp8b2	XP_021322579.1	P-type_ATPase_APLT_Dnf-like	63..1033	CDD:319770	377/1160 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920