Protein Alignment CG33298 and Atp10b

DIOPT Version :10

• Sequence 1: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: NP_795973.2
• Gene: Atp10b / 319767
• MGIID: 2442688
• Length: 1474
• Species: Mus musculus
• Alignment Length: 1452
• Identity: 563/1452 - (38%)
• Similarity: 808/1452 - (55%)
• Gaps: 255/1452 - (17%)

  Fly   207 W--WKRLTLCNYNTGDKFEERSYRTVVPNHTVP---PKTPKRDH---------PNG--------- 248
            |  ||      :.|.|.|.:.      |:.|.|   |:|.::.|         ||.
Mouse     9 WLRWK------WRTQDGFSQS------PSETTPLLSPETDRQSHNTAEQRVVYPNNSMCHQDWKK 61

  Fly   249 ---QFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVL 310
               ::.||.|.|||||||:|:|:||.|||||.|||||:|:|:|||:|.:..|.:|:.:.|:..||
Mouse    62 VCRRYPGNSICTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITIFPLATVL 126

  Fly   311 GVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLL 375
            .:..|||..||.:|...|:.:|:.:.::|:.:.:||...:||::||||.|.:..||.||||||||
Mouse   127 LIIMVKDGIEDFKRYCFDREMNSASIQIYERKEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLL 191

  Fly   376 RTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHGALIH 440
            .:|||.|||:::|.:||||||||:|.||:||.:.:..|.|..|.|.:..:.|...|.:|.|.:.|
Mouse   192 FSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEHFHSTIVCEKPNNHLSKFKGYMEH 256

  Fly   441 PTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCV 505
            |...|....:|.||||...::||:...|||:|||||||:||||||||||||::|:::|.|:.:|:
Mouse   257 PDQTRTGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCI 321

  Fly   506 IILLILCVVGAIGCRMWLSSFTHFP---VPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVT 567
            .:|.::|::||:|..:|..:|...|   ||....|.|:..:...::|.|.|::|||:||:||||:
Mouse   322 GLLFLMCLIGAVGHSLWNGTFKEHPPFDVPDADGNFLSLALGGFYMFLTMIILLQVLIPISLYVS 386

  Fly   568 IELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVN 632
            |||.|:.|||.:||::||:|.||:...:|||:||||:|||||:||:|||||||||||:||||.:.
Mouse   387 IELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIV 451

  Fly   633 GSDYNHP--------PSELEK-----------------------IYSKPGA-------------- 652
            ||:|.|.        |.||:.                       :.|:.||
Mouse   452 GSEYCHQENAKRLEMPKELDSDGEEWTQYQCLSFPPRWAQGSTTMRSQGGAQPLRRCHSARVPIQ 516

  Fly   653 -------------PAPP----------LIPNDNLNSDM--AQLTQGTYLTPHAQ-------RIQE 685
                         ..||          :.|:.||.|.:  |.|...|..|..|:       .|.:
Mouse   517 SHCRQRSVGRWETSQPPVAFSSSIEKDVTPDKNLLSKVRDAALWLETSDTRPAKPSHSTTASIAD 581

  Fly   686 FLVVLAICNTVIVGAA--PHRDMMNASGIIEVQQIGNSPANLKHGK---------QRQKLLASST 739
            |.:.|.|||:|:|...  |.:            ::...|||...|.         ||.|||:.|.
Mouse   582 FFLALTICNSVMVSTTTEPRK------------RVTTPPANKALGTSLEKIQQLFQRLKLLSLSQ 634

  Fly   740 STTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAES 804
            |.::|.               |:|  ..|.||..      |||          ||:.
Mouse   635 SFSSTA---------------PSD--TDLGESLG------PNL----------PTID-------- 658

  Fly   805 SPNSESESPSPPMKNKSLSNSI-SPTGRAKAVINSKI-TSIATFLNAKTQGKRMKLPSSKTGTIY 867
              :.|.:..|....:.|..... |.|.....::.|:. ||:...|.|.|
Mouse   659 --SDEKDDTSVCSGDCSTDGGYRSSTWEQGDILGSESGTSLEEGLEAPT---------------- 705

  Fly   868 RTADGRP--LYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSR 930
             .:...|  .||||||||.|||:||.:|...|::|:|.|:.|.:|. |....:::|..|.|||.|
Mouse   706 -LSQDEPELCYEAESPDEAALVHAARAYSFTLVSRTPEQVTVRLPQ-GICLTFDLLFTLGFDSVR 768

  Fly   931 KCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGI------LREQTQQLLDRYAREGLR 989
            |.||:|||...:.||::|||||||.||.:|...:..|...:      :|.:||:.||.|||:|||
Mouse   769 KRMSVVVRHPLTDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLR 833

  Fly   990 ILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPET 1054
            .|.:||:.::..|:..|.:..:|.|.||:|||..|.::...||::||||||||||||||:|||:|
Mouse   834 TLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDT 898

  Fly  1055 IASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKT 1119
            ||:|..|||.:|||||||.|||:|||||.||..|...:..:...:::..|:.:|..|.|::....
Mouse   899 IAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCESILNCTLEDIKRFHE 963

  Fly  1120 TSTLGYGQSLRK-------------------KQRALVVDGKTLTFILDPKSKLILPFLRLSKRCA 1165
            ..     |..||                   .:..||:|||||..|.  :.||...||.|::.|.
Mouse   964 PQ-----QPARKLCGHRIPPKMPSVNSGAMAPEIGLVIDGKTLNAIF--QGKLENKFLELTQYCR 1021

  Fly  1166 SVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTL 1230
            ||||||||||||:.:||:|:::|::.||:||||||||||||.||:|:||||||||||||::||.:
Mouse  1022 SVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAI 1086

  Fly  1231 PRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLI 1295
            .||.:|::|||.||:|||.||:||::|:||||..:|.|:||||.:|||||..|:|...::.:||.
Mouse  1087 ARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLF 1151

  Fly  1296 FTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYA 1360
            ||||||:..||.||.|:.:.||..|.|||:|:....|....||:.:.||.||||:.||:....|.
Mouse  1152 FTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYR 1216

  Fly  1361 ESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVR 1425
            .||:.::.|||.|....|...|:|.|:|:::|||||.|.::.|...:::.:::|::.|:.|....
Mouse  1217 GSDIDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLMYFVVSLIYNATCVTCNSPT 1281

  Fly  1426 SSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTV-------------RISLCPDDSTKVILQS 1477
            :.|||:....:....:|:.:|:.|||:|||..|.::             :|...|.|...:.:|:
Mouse  1282 NPYWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKAQKIDKLPIDKRNLEIQN 1346

  Fly  1478 KRERSRGEALLVTWSRSTSASS 1499
            .|.:.|....    |.|.|||:
Mouse  1347 WRSKQRPAPA----SASASASA 1364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	504/1222 (41%)
Atp10b	NP_795973.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..43		7/29 (24%)
		P-type_ATPase_APLT_Dnf-like	68..1211	CDD:319770	504/1222 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	638..707		22/128 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1348..1421		7/21 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1434..1474