Protein Alignment CG33298 and Atp8b3

DIOPT Version :10

• Sequence 1: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: NP_001419373.1
• Gene: Atp8b3 / 299616
• RGDID: 1307622
• Length: 1340
• Species: Rattus norvegicus
• Alignment Length: 1316
• Identity: 399/1316 - (30%)
• Similarity: 625/1316 - (47%)
• Gaps: 284/1316 - (21%)

  Fly   249 QFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVT 313
            ::..|.|.|.||.:.||:|.||.|||.||:||||:||::|..:||||.........|::.:|.:.
  Rat    44 KYKSNAIHTAKYNVFSFLPLNLYEQFRRVSNLYFLFIIILQSIPEISTLPWFTLFAPLVCLLMIR 108

  Fly   314 AVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTS 378
            |.:||.:|..|..||:.|||..|::..|::..:|  ||:.|.|||:|.||.:..||||:|||.::
  Rat   109 AARDLVDDIGRHRSDRIINNRPCQILKGKSFLWK--KWKNLCVGDVVCLSKDNIVPADLLLLAST 171

  Fly   379 DPQGVCYIDTCDLDGETNLK-RREVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHGALIHPT 442
            :|..:||::|.|:||||||| |:.::....|:.|....:.|...|..:.|.::::.|.|:| ...
  Rat   172 EPSSLCYLETADIDGETNLKFRQALMVTHHELTSPKKMASFQGIVTCEEPNSRMHHFVGSL-EWN 235

  Fly   443 GERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVII 507
            ..:.|:....||||..:::|||...|:|:|||.:||.|.|......||::::..||..||...:.
  Rat   236 SRKYPLDIGNLLLRGCKIRNTDTCYGLVIYAGLDTKIMKNCGKIHLKRTKLDLMMNKLVILIFMS 300

  Fly   508 LLILCVVGAIGCRMWLSSF--THFPVPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIEL 570
            |:|..:...:|....:..|  .|..:..:...  |..|:|.:|||.::::|.||:|:::::..|.
  Rat   301 LVIASMFLTLGFAFMVKEFKAKHHYMSSMQGR--TDAMDSFFIFWGFLILLSVMVPMAMFIIAEF 363

  Fly   571 CKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNG-- 633
            ..:.....|:.::.::....:...:.|:.::.:.|||:|:||:|||||||:|.|.|::|.:||
  Rat   364 IYLGNSIFINWDLSMYYEPLDIPAKARSTSLNDHLGQVQYIFSDKTGTLTQNIMTFKKCCINGCT 428

  Fly   634 --SDYNHPPSELEKIYS-KPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNT 695
              ||..|........|| .|.|.......|..|.|    |.:|    ...:.:|||..:||||:|
  Rat   429 YDSDDEHGTLRKRNPYSWNPFADGKLQFYNKELES----LVRG----KQDRAVQEFWRLLAICHT 485

  Fly   696 VIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSI 760
            |:|
  Rat   486 VMV-------------------------------------------------------------- 488

  Fly   761 PADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNS 825
                                                                             
  Rat   489 ----------------------------------------------------------------- 488

  Fly   826 ISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYEAESPDELALVNAA 890
                                                      :..|.:.||:|.||||.|||.||
  Rat   489 ------------------------------------------QEKDNQLLYQAASPDEEALVAAA 511

  Fly   891 YSYDCCLLNRSPNQI-LVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQ-IGSQEIVLYTKGAD 953
            .::....|:|:.:.| ||.:   |..|.|::|.::.|:|.||.||::||. .||  |.|||||||
  Rat   512 RNFGYVFLSRTQDTITLVEL---GEERVYQVLAMMDFNSVRKRMSVLVRNPEGS--ICLYTKGAD 571

  Fly   954 SSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLE 1018
            :.|:..|    |:  :|::...|:::|..:|.:.||.|.:|.:.:....|.:|...|||..:.|:
  Rat   572 TVILERL----HH--KGVMEATTEEVLAAFAEQTLRTLCLAYKDVAEDAYKEWEPEHQEAALLLQ 630

  Fly  1019 NRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSA 1083
            ||.:.|...:.|||.||.|||.|.|||:|||||||||..|....|.:|||||||||||:||.::.
  Rat   631 NRAQALHQVYNKLEQNLQLLGVTAIEDKLQDGVPETIRCLKKGNIKMWVLTGDKPETAVNIGFAC 695

  Fly  1084 KLFTQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTLGY--------GQ-------SLRKKQ 1133
            :|.::.|.::    ..:|......| |..:.|:.:...|:.:        |:       ||||:.
  Rat   696 QLLSENMSIL----EDKDIKGLLEN-YWDENEHQRAFQTMTHHNMALVINGEFLDQLLLSLRKEP 755

  Fly  1134 RAL----VVDGKT-------LTFIL---------------------------DPKSKLILPFLRL 1160
            |||    |||..|       |.|:.                           .|:.:....|:.|
  Rat   756 RALVQNAVVDEATQEPGVSALDFLQARRISQMWRNFGTTMATSQSDASKTRESPEERRERAFVDL 820

  Fly  1161 SKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMA 1225
            :.:|.:|:|||.||.|||.:|.:||:...:.|||||||||||:||:.||:|||::||||||||..
  Rat   821 ASKCQAVICCRVTPKQKALVVALVKKYQQVVTLAIGDGANDVNMIKTADIGVGLAGQEGMQAVQN 885

  Fly  1226 ADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLM 1290
            :|:.|.:|.||:||||.||.|.|.|:.:.:.|||||..|.:....|:.|:.|||.|.:.:..:|.
  Rat   886 SDYVLAQFCYLQRLLLVHGRWSYMRICKFLRYFFYKTVASMMAQIWFSLFNGFSAQPLYEGWFLA 950

  Fly  1291 LYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVA 1355
            |:||::::||.|.||::::.|..:..||.|.||..|:....:....|...:......||:.|||.
  Rat   951 LFNLLYSTLPVLYIGLFEQDVTAEKSLKMPELYTAGQKDELFNYSIFVQAIAHGTITSLINFFVT 1015

  Fly  1356 -LCAYAESDVG----IWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYD 1415
             |.:|..:..|    ...||..:..|.|.:..:...:.::.||:|.|.::|:||.|:.:|..:.:
  Rat  1016 ILVSYDMTKTGSSPDYQSFGVLVAISSLLSITLEVILVVKYWTLLFVGTVVVSLSSYVIFTSLTE 1080

  Fly  1416 SVCMNCFGVRSSYWVIFVCFASAVH----WLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKVILQ 1476
            |:.:  |.:....:.......:.:.    .|||:|:..:..||.|.:..:|         :.:|:
  Rat  1081 SLLL--FRISPKTFPFLFADYNVIREPSSLLVIVLNVTLNTLPMLAVRIIR---------RTVLK 1134

  Fly  1477 ---SKRERSRGEALLV 1489
               .|.|....|.|.|
  Rat  1135 RHPKKEEEVPSEELTV 1150

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	366/1165 (31%)
Atp8b3	NP_001419373.1	P-type_ATPase_APLT_Dnf-like	47..1015	CDD:319770	366/1165 (31%)