Protein Alignment CG33298 and tat-2

DIOPT Version :10

• Sequence 1: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: NP_001294447.1
• Gene: tat-2 / 177256
• WormBaseID: WBGene00019166
• Length: 1349
• Species: Caenorhabditis elegans
• Alignment Length: 1390
• Identity: 410/1390 - (29%)
• Similarity: 644/1390 - (46%)
• Gaps: 331/1390 - (23%)

  Fly   162 LPP--GHKEEPAREPSAPTSATGGRGH-------SRQASRSESIYTLRRTEAPPWWKRLTLCNYN 217
            :||  .:.::|..|.|..::..||.|.       ....|..::..|.||..|
 Worm     9 VPPQQAYNDKPKEESSTKSAKKGGGGGMFSWLPCCSSTSNEKNAPTERRLRA------------- 60

  Fly   218 TGDKFEERSYRTVVPNHTVPPKTPKRDHPNGQF--VGNKIRTTKYTLLSFIPKNLLEQFHRVANL 280
                 .:|.|                   |.||  ..|.|:|:||.:::|||:||.|||.|:||.
 Worm    61 -----NDREY-------------------NAQFKYADNVIKTSKYNIITFIPQNLFEQFQRIANF 101

  Fly   281 YFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETER 345
            ||:.:::|.::|:||:.......:|::.||..:|:||.::|.:|..||:.:|..  :.|......
 Worm   102 YFLVLMILQFIPQISSISWYSTAVPLVIVLAFSAIKDGYDDAQRHISDRNVNGR--KSYVVRNGS 164

  Fly   346 YKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEM- 409
            ..:..|..::|||::.:.:|:.|.||:|||.||:|.|||:|:|.:||||||||.|..:...:||
 Worm   165 LCEEDWSNVKVGDVIRMMSNQFVAADLLLLSTSEPYGVCFIETMELDGETNLKNRAAIACTQEMG 229

  Fly   410 QSIFVPSKFVSRVEADAPTTKLYRFHGALI---HPTGERVPISTECLLLRESRLKNTDYIEGIVV 471
            ..:...::|...:..:.|..||.:|:|.||   |..|    ::.:.:|||...||||.:..|:||
 Worm   230 DDLDGITRFDGEIICEPPNNKLDKFNGKLIWNNHEYG----VNNDNILLRGCILKNTRWCYGVVV 290

  Fly   472 YAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPP 536
            :||.:||.|:|:...::||:.:::.:||.::..|:.|:.:|::..|.|.:|......:...|||.
 Worm   291 FAGKDTKLMMNSGKTKFKRTSLDRFLNILIVGIVLFLIAMCLICTILCAVWEYQTGRYFTIYLPW 355

  Fly   537 NKLTANME----------SMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETN 591
            :.:..:.|          :...|::||::|..::|:||||::|:.:.:....|:.:..::.....
 Worm   356 DDVVPSPEQRGGRQIALIAFLQFFSYIILLNTVVPISLYVSVEIIRFIHSLWINYDTQMYYENGE 420

  Fly   592 KQTECRAMNIT--EELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDY-------------NHPPS 641
            |....:|...|  |||||:|::|:|||||||.|.|.|.:|.:||..|             |....
 Worm   421 KSVPAKAHTTTLNEELGQVQYVFSDKTGTLTRNIMTFNKCTINGISYGDIYDHKGEVIETNDKTK 485

  Fly   642 ELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDM 706
            .|:..::....|.......:.:::...|:.:          |.:|..:||:|:||:    |.||
 Worm   486 SLDFSWNSASEPTFKFFDKNLVDATKRQVPE----------IDQFWRLLALCHTVM----PERD- 535

  Fly   707 MNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAES 771
                                                                             
 Worm   536 ----------------------------------------------------------------- 535

  Fly   772 RSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVI 836
                                                                             
 Worm   536 ----------------------------------------------------------------- 535

  Fly   837 NSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRS 901
                                              .|:.:|:|:||||.||.:||.::......|:
 Worm   536 ----------------------------------KGQLVYQAQSPDEHALTSAARNFGYVFRART 566

  Fly   902 PNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQ-EIVLYTKGADSSIMPVLVPCSH 965
            |..|.:.  :.|....:|:|.:|.|::.||.||::|:  |.. :|.||.||||..||..:    |
 Worm   567 PQSITIE--VMGNEETHELLAILDFNNDRKRMSVIVK--GPDGKIRLYCKGADMMIMQRI----H 623

  Fly   966 NSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAK 1030
            .|...|:|..|...|..:|..|||.|.:..:.|:.|.::||.:|.::...::::||..:...:.:
 Worm   624 PSTSQIMRTSTNTHLADFANIGLRTLCLGYKDLDPAYFSDWDSRVKKASAAMQDRESAVDALYEE 688

  Fly  1031 LESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRL 1095
            :|.:|.|:|||.|||:|||||||.||.|..|.|.:|||||||.|||||||||.:|.|.:.:.|.:
 Worm   689 IEKDLILIGATAIEDKLQDGVPEAIARLSEANIKIWVLTGDKTETAINIAYSCRLLTDETKEIVV 753

  Fly  1096 TARSRDAAETAINFYLTDMEND-----KTTSTLGYGQ----------------SLRKKQR----- 1134
            .....|   |.:...|.|..|.     ...|.|| |:                |.|...|
 Worm   754 VDGQTD---TEVEVQLKDTRNTFEQILALPSPLG-GKPRIEIETIHEESEAISSARSMDRNIVTP 814

  Fly  1135 ---------------ALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVV 1184
                           |||::|.:|.|.|.|  :|...||.::..|.:|:|||.||||||.:|.:|
 Worm   815 DLKSAEMAEHESGGVALVINGDSLAFALGP--RLERTFLEVACMCNAVICCRVTPLQKAQVVDLV 877

  Fly  1185 KEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYD 1249
            |......||:|||||||||||:.|.:|||||||||||||:|:|:::.:|:|||||||.||.|.|.
 Worm   878 KRNKKAVTLSIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSIGQFKYLERLLLVHGRWSYI 942

  Fly  1250 RLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAED 1314
            |:::.:.||||||.||....|||..:||:|.|.:.|.:.:..|||.||:||.||:|..|:.|.:.
 Worm   943 RMAKFLRYFFYKNFAFTLTNFWYSFFCGYSAQTVFDAVLIACYNLFFTALPVLAMGSLDQDVDDH 1007

  Fly  1315 LLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAY----AESDVGIWEFG----T 1371
            ..|:.|.||..|:..:.:....|...:|..::.||||||:...|:    |.|...:.::.    |
 Worm  1008 YSLRYPKLYLPGQFNLFFNMRIFIYSVLHGMFSSLVIFFIPYGAFYNAAAASGKDLDDYSALAFT 1072

  Fly  1372 TITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFA-IVYDSVCMNCFGVRS---SYWVIF 1432
            |.||..:... ...|.:...||.:....|..||..::|.. ::|:.:.::.....|   ||.|.|
 Worm  1073 TFTALVVVVT-GQIAFDTSYWTAISHFVIWGSLVLYFLVCFLLYEWLPVSWIVKTSSSISYGVAF 1136

  Fly  1433 VCFASAVHWLVIMLSTVVAVLPRLL 1457
            ....:...|..|::.:||.:||.:|
 Worm  1137 RTMVTPHFWFSILMVSVVLLLPVML 1161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	365/1173 (31%)
tat-2	NP_001294447.1	P-type_ATPase_APLT_Dnf-like	73..1048	CDD:319770	365/1173 (31%)