Protein Alignment CG33298 and LOC1277786

DIOPT Version :10

• Sequence 1: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: XP_061518483.1
• Gene: LOC1277786 / 1277786
• VectorBaseID: AGAMI1_003457
• Length: 1155
• Species: Anopheles gambiae
• Alignment Length: 1361
• Identity: 382/1361 - (28%)
• Similarity: 623/1361 - (45%)
• Gaps: 262/1361 - (19%)

  Fly   156 SKTDFILPPGHKEEPAREPSAPTSATGGRGHSRQASRSESIYTLRRTEAPPWWKRLTLCNYNTGD 220
            |:|:.::.|           |...|....|.|.:..|.||.      :...:.|:|..|......
Mosquito    13 SETELLIEP-----------ATARANRLNGRSFRNRRQESF------KLGSFLKKLCCCWCWAWR 60

  Fly   221 KF---EERSYRTVVPNHTVPPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYF 282
            |:   :|...||:.....:..|.|.          |:||..||...:|:|..|.|||....||||
Mosquito    61 KWCASKELKPRTIYIGRPLTEKFPP----------NEIRNQKYNFFTFLPLVLFEQFRFFLNLYF 115

  Fly   283 IFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYK 347
            :.:.:..::|||..........|:.|||.||..::..:|.||...|:.:|:...:.:....:..:
Mosquito   116 LIMAVSQFIPEIRIGYLYTYWGPLGFVLAVTICREAVDDLRRHKRDREVNSQKYKRFVSADKPPE 180

  Fly   348 KVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQS- 411
            .|...:||||||:.:..:|.||||::||||||..|..::.|..|||||:.|.|..|...:::.|
Mosquito   181 SVSSSKLRVGDIIMVEKDERVPADLILLRTSDKSGAVFVRTDMLDGETDWKLRLAVPATQKLASH 245

  Fly   412 ----IFVPSKFVSRVEADAPT-TKLYRFHGALIHPTGERVPISTECLLLRESRLKNTDYIEGIVV 471
                ....|.:|.:.:.|..| ...|..||..     |...::.|..|...:.:.:...: |||:
Mosquito   246 GELLTVNASLYVEKPQRDIHTFIGTYSKHGGT-----EDEGLNVENTLWANTVVASGTAV-GIVI 304

  Fly   472 YAGHETKSMLNNSGPRYKRSQVEQQMN--IDVIWCVIILL---ILCVVGAIGCRMWLSSFTHFPV 531
            |.|.||:|::|||.||.|...::.::|  ..|::|.:|.|   ::|:.|..|  .|..
Mosquito   305 YTGSETRSVMNNSQPRSKVGLLDLEINNLTKVLFCAVIGLSFAMMCLKGFNG--PWYR------- 360

  Fly   532 PYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTEC 596
             |:               :.::::...:||:||.|.:::.|....:.|.|:.::      |.|..
Mosquito   361 -YM---------------FRFVLLFSYIIPISLRVNLDMGKAFYSWQIQNDDEI------KGTVV 403

  Fly   597 RAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHP-----PSELEKIYSKPGAPAPP 656
            |:..|.||||::.::.||||||||:|:|||::..|..:.|...     .:.::.:|....||| .
Mosquito   404 RSTTIPEELGRMSYLLTDKTGTLTQNEMIFKKIHVGTAAYGRDTFPMVSAAIQSVYGTLSAPA-D 467

  Fly   657 LIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASG----IIEVQQ 717
            ..|.|:.:....:|.:     |...||.|.:..||:|:.|    .|..:..|.:|    |.....
Mosquito   468 ASPEDHGSEYQPRLRK-----PDGWRIWESVKALALCHNV----TPVYESNNGNGGSGSISSTSD 523

  Fly   718 IGNSPA-NLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPN 781
            ...||| ::....|..:...|..:||..|.    ..:.|..:::     ::..||..:|
Mosquito   524 RRQSPARSISVESQAGEPSTSKPATTEKTY----QASSPDEIAL-----VKWTESVGLT------ 573

  Fly   782 LLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATF 846
               .:....:..||....::.|:...|.:|:.|                     ||:.:|:::
Mosquito   574 ---LVQRDLNHMTLQIRDATHEARGTSMNENAS---------------------INTTVTNLS-- 612

  Fly   847 LNAKTQGKRMKLPSSKTGTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPM 911
            :|:||.   :..||| .|::                                 .|.|.|:.
Mosquito   613 VNSKTD---LNSPSS-GGSV---------------------------------TSLNSIIA---- 636

  Fly   912 AGA--TREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILRE 974
            |||  ..:|:||:..||.|..|.|.|:||::...||..|.|||| .:|..:|  .:|.   .|.|
Mosquito   637 AGAPGLMKYQILQTFPFTSENKRMGIIVRELNGGEITFYLKGAD-VVMSGIV--QYND---WLAE 695

  Fly   975 QTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLG 1039
            ::..:    ||||||.||:||:.|:...|.|:..|:...::|:.:|..::......||..:.||.
Mosquito   696 ESGNM----AREGLRTLVVAKKVLSEEQYNDFVMRYNAAKVSVTDRVAKVAAVIESLEREMELLC 756

  Fly  1040 ATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAE 1104
            .||:||||||.|..|:..|.:|||.:|:|||||.|||..||.|:.|.            .|:.:.
Mosquito   757 LTGVEDRLQDRVRPTLELLRNAGIKIWMLTGDKLETATCIAKSSHLV------------GRNQSI 809

  Fly  1105 TAINFYLTDMENDKTTSTLGYGQSLRKKQRALVVDGKTLTFIL---DPKSKLILPFLRLSKRCAS 1166
            ..:...||     :|.:.|...|..||:..||||.|::|...|   .|:      |:.|:..|.:
Mosquito   810 HVLKSVLT-----RTDAHLELNQFRRKQDCALVVSGESLEVCLQYYQPE------FMELATACPA 863

  Fly  1167 VLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLP 1231
            |:|||.:|.|||.:|.::::....||.|:|||.|||||||.||.|:||.|:||.||.:|.||::|
Mosquito   864 VVCCRCSPTQKAQVVSLIQKYSKKRTCAVGDGGNDVSMIQQADAGIGIEGREGKQASLAGDFSIP 928

  Fly  1232 RFRYLERLLLAHGYWCYDRLSRMILYFFYK-------NAAF--VFLIFWYQLYCGFSGQVMMDQM 1287
            :|.::.|||:.||...|.|.:.:..:..::       .|.|  ||.:....||.||
Mosquito   929 QFSHIARLLIVHGRRSYKRSAALSQFVIHRGLIISTMQAVFSAVFYLSSVALYQGF--------- 984

  Fly  1288 YLML-YNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYK---NGRLGVAYRPHDFWLILLDALYQS 1348
             ||: |..::|..|..:: |.|:.::.::.:..|.|||   .|| .::|:....|:::  ::||.
Mosquito   985 -LMVGYATLYTMFPVFSL-VLDQDISANIAITYPELYKELSKGR-SLSYKTFFMWVLI--SIYQG 1044

  Fly  1349 LVIFFVALCAYAESDVGIWEFGTTITASCL-FANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAI 1412
            .||.:.||..:.:..:.|    ..|:.|.| ...|:..|:.||:|   |.|.::..|.|..|:.:
Mosquito  1045 GVIMYGALILFEDEFIHI----VAISFSALILTELIMVALTIRTW---HKLMVIAELFSLVLYIV 1102

  Fly  1413 VYDSVCMNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKV 1473
                    ...|...|:.....::....|.|::: |:|:.||..:|..:|....|...:|:
Mosquito  1103 --------SLAVLHEYFDWEFIWSWDFLWKVLVI-TLVSCLPLYILKFLRKKFSPPSYSKL 1154

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	335/1141 (29%)
LOC1277786	XP_061518483.1	None