Protein Alignment CG33298 and Atp10a

DIOPT Version :10

• Sequence 1: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Sequence 2: NP_033858.2
• Gene: Atp10a / 11982
• MGIID: 1330809
• Length: 1508
• Species: Mus musculus
• Alignment Length: 1415
• Identity: 582/1415 - (41%)
• Similarity: 808/1415 - (57%)
• Gaps: 216/1415 - (15%)

  Fly   167 KEEPAREPSAPTSATGGRGHSRQASRSESIYTLRRTEAPPWWKRLTLCNYNTGDKFEERSYRTVV 231
            :|.||.|.||   ::|.|...|           ||      |:..|               |||.
Mouse     3 RELPAAEESA---SSGWRRPRR-----------RR------WEGRT---------------RTVR 32

  Fly   232 PNHTVPP---KTPKRDHPNGQ----------FVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFI 283
            .| .:||   :......|.|:          ...|:::|||||||||:||||.|||||:||:||:
Mouse    33 SN-LLPPLGTEDSTIGAPKGERLLMRGCIQHLADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFV 96

  Fly   284 FIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKK 348
            ||.|||:||.::||...:|:.||||:|.|||:|||:||..|..||..||:..|.|:..|.::|..
Mouse    97 FIALLNFVPAVNAFQPGLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSREEKKYVN 161

  Fly   349 VKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIF 413
            ..|:|:||||.|.|..||.:|||||||.:|||.|:|:|:|.:||||||||||:|||||.|:.|.|
Mouse   162 RYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEF 226

  Fly   414 VPSKFVSRVEADAPTTKLYRFHGALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETK 478
            .|..|.|.:|.:.|...|.||.|.::|..||:..:..|.||||...::||:.:.|||:|||||||
Mouse   227 NPLTFTSVIECEKPNNDLSRFRGYIMHSNGEKAGLHKENLLLRGCTIRNTEAVAGIVIYAGHETK 291

  Fly   479 SMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTH----FPVPYLPPNKL 539
            ::||||||||||||:|:|||.||:|||::|:.:.:..|:|..:|:..:..    |.||....:.|
Mouse   292 ALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRRYQEKKALFDVPESDGSSL 356

  Fly   540 TANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEE 604
            :....:::.|:|.|::|||:||:||||:||:.|:.||:.|:.:::|:|.||:.|.:|||:||||:
Mouse   357 SPATAAVYSFFTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITED 421

  Fly   605 LGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNH------------PPSELEKIYSKPG------ 651
            ||||::||:|||||||||||:||||.|:|.:|:|            ..||.|::.||.|
Mouse   422 LGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLARYQEADSEEEEVVSKVGTISHRG 486

  Fly   652 ---------------------------------------APAPP----LIPNDNLNSDMAQLTQG 673
                                                   |.:.|    :.|:..|...:::..:.
Mouse   487 STGSHQSIWMTHKTQSIKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDRF 551

  Fly   674 -----------TYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKH 727
                       .:|:|....:.:|.:.|.|||||:|                     .||
Mouse   552 LAIARHQEHPLAHLSPELSDVFDFFIALTICNTVVV---------------------TSP----- 590

  Fly   728 GKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQ 792
            .:.|||:.......:...||               :.::     |..|||         ...|..
Mouse   591 DQPRQKVRVRFELKSPVKTI---------------EDFL-----RRFTPS---------RLASGC 626

  Fly   793 PTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMK 857
            .::..:|:|..|..:..:..|       |||......| .:..:.....|||:...|...|:...
Mouse   627 SSIGNLSTSKSSHKSGSAFLP-------SLSQDSMLLG-LEEKLGQTAPSIASNGYASQAGQEES 683

  Fly   858 LPSSKT------GTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATR 916
            ..|..|      |......:|...||||||||.|||.||.:|:|.|::|..:|:.|.:|..|..
Mouse   684 WASECTTDQKCPGEQREQQEGELRYEAESPDEAALVYAARAYNCALVDRLHDQVSVELPHLGRL- 747

  Fly   917 EYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEG----ILREQTQ 977
            .:|:|..|.|||.||.||:|:|...:.||.:|||||||.:|.:|:|||.:...|    .:|.:||
Mouse   748 TFELLHTLGFDSIRKRMSVVIRHPLTDEINVYTKGADSVVMDLLLPCSSDDARGRHQKKIRSKTQ 812

  Fly   978 QLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATG 1042
            ..|:.||.||||.|.:|||.|:..:|..|...|.|.|.|:|:||..|..|..:||:||.||||||
Mouse   813 NYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAEASVESREELLFQSAVRLETNLHLLGATG 877

  Fly  1043 IEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAI 1107
            ||||||:|||||||.|..||:.:|||||||.||||||||:.||.....|:|.|.|.|::|....:
Mouse   878 IEDRLQEGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSQEACAALL 942

  Fly  1108 NFYLTDMENDKTTSTLGYGQSL---------------RKKQRALVVDGKTLTFILDPKSKLILPF 1157
            :..|:.:::....|||...:|.               .....:||:||::|.:.|:  ..|...|
Mouse   943 DQCLSYVQSRNPRSTLQNSESNLSVGFSFNPVSTSTDASPSPSLVIDGRSLAYALE--KSLEDKF 1005

  Fly  1158 LRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQA 1222
            |.|:|:|.||||||||||||:.:||:|:.:|...|||||||||||||||:|||||||||||||||
Mouse  1006 LFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQA 1070

  Fly  1223 VMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQM 1287
            |||:||.:||||||||||:.||:|||.||:.|:|||||||..||.|:||:|.|||||...|:||.
Mouse  1071 VMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQW 1135

  Fly  1288 YLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIF 1352
            ||:.:||:|:|||.|..||.||.|..|:||:.|.|||:|:....|||..|||.::||.:||||.|
Mouse  1136 YLIFFNLLFSSLPQLVTGVLDKDVPADMLLREPQLYKSGQNMEEYRPRAFWLNMVDAAFQSLVCF 1200

  Fly  1353 FVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSV 1417
            |:...||.:|||.::.:||.:||..||..|:|..||.::||.|:.|:...|...|:..|::|::.
Mouse  1201 FIPYLAYYDSDVDVFTWGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFLFFSVALIYNTS 1265

  Fly  1418 CMNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCP 1467
            |..|:...:.||.:.......:.:|..:::.:.|:||||....::.||.|
Mouse  1266 CATCYPPSNPYWTMQTLLGDPLFYLTCLIAPIAALLPRLFFKALQGSLFP 1315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	525/1203 (44%)
Atp10a	NP_033858.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		9/33 (27%)
		P-type_ATPase_APLT_Dnf-like	65..1203	CDD:319770	525/1203 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	680..705		3/24 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1334..1354
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1407..1436
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1481..1508