Protein Alignment CG18420 and Cfd

DIOPT Version :10

• Sequence 1: NP_995715.1
• Gene: CG18420 / 2768924
• FlyBaseID: FBgn0028866
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_001071110.1
• Gene: Cfd / 54249
• RGDID: 2498
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 254
• Identity: 65/254 - (25%)
• Similarity: 114/254 - (44%)
• Gaps: 43/254 - (16%)

  Fly    42 RIVNGKVAVRNSSPWMAFLHTSSNQFICGGTLISRRLVLTAAHCF---IPNTTIVVRLGEYN-RK 102
            ||:.|:.|:.::.|:||.:..:... :|||||:..:.||:||||.   ..:..:.|.||.:: ..
  Rat    25 RILGGQEAMAHARPYMASVQVNGTH-VCGGTLVDEQWVLSAAHCMDGVTKDEVVQVLLGAHSLSS 88

  Fly   103 LKGYREEHQVNRTFQHRFYDPNTHANDIALLRLVSNVVYKANIRPICIMWDASWKHHIDSIKVLT 167
            .:.|:..:.|.....|....|::..:|:.|.:|..|.....::||:.:        ..:..:|..
  Rat    89 PEPYKHLYDVQSVVLHPGSRPDSVEDDLMLFKLSHNASLGPHVRPLPL--------QREDREVKP 145

  Fly   168 GT-----GWG-RTESMHDSSELRTLDISRQPSKMCAF-----GSVLSNQFCAGNWNSNLCIGDTG 221
            ||     ||| .|.:......|:.|.:|......|..     |::..|..||.:...:.|.||:|
  Rat   146 GTLCDVAGWGVVTHAGRRPDVLQQLTVSIMDRNTCNLRTYHDGAITKNMMCAESNRRDTCRGDSG 210

  Fly   222 GP------VGAMVRYRNAFRFVQVGIAITNKRCQRPSVFTDVMSHIEFIRRIFLTQNGN 274
            ||      |.|:|.:         |..:...| ::|.|||.|.:::.:|..:.   :||
  Rat   211 GPLVCGDAVEAVVTW---------GSRVCGNR-RKPGVFTRVATYVPWIENVL---SGN 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18420	NP_995715.1	Tryp_SPc	42..264	CDD:214473	62/242 (26%)
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	62/244 (25%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/12 (8%)