DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18420 and CG9737

DIOPT Version :9

Sequence 1:	NP_995715.1	Gene:	CG18420 / 2768924	FlyBaseID:	FBgn0028866	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_651783.1	Gene:	CG9737 / 43600	FlyBaseID:	FBgn0039758	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	86/318 - (27%)
Similarity:	137/318 - (43%)	Gaps:	81/318 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TVFPLLGSTQFLDSECGTRSPLKLGPRIVNGKVAVRNSSPWMAFLHTSSNQFICGGTLISRRLVL 80
            ||.|..|..  |.:|||.    ::..||..|::|..:..||:|.|..:||.:.|.|.||..|.:|
  Fly   129 TVEPSSGFN--LLNECGK----QVTNRIYGGEIAELDEFPWLALLVYNSNDYGCSGALIDDRHIL 187

  Fly    81 TAAHCFIPNTTI-------VVRLGEYNRKLK-------------------GYREEHQVNRTFQHR 119
            ||||| :....:       .|||||:|.|.:                   .|.:.|      .|.
  Fly   188 TAAHC-VQGEGVRDRQGLKHVRLGEFNVKTEPDCIEEPNYLSCADAALDIAYEKIH------VHP 245

  Fly   120 FYD--PNTHANDIALLRLVSNVVYKANIRPICIMWDASWKHHIDSIKVLTG-----TGWGRTE-- 175
            .|.  .|...||||::||...|.:...:.|||:      .:..:.:.:..|     :|||||:
  Fly   246 EYKEFSNYKYNDIAIIRLKHPVSFTHFVMPICL------PNKSEPLTLAEGQMFSVSGWGRTDLF 304

  Fly   176 -----SMHDSSELRTLDISRQPSKMC-----AFGSVLS-NQFCA-GNWNSNLCIGDTGGPVGAMV 228
                 ::|...:|: |.|....::.|     .||..|. .|.|| |.:..:.|.||:|||:....
  Fly   305 NKYFINIHSPIKLK-LRIPYVSNENCTKILEGFGVRLGPKQICAGGEFAKDTCAGDSGGPLMYFD 368

  Fly   229 RYRN--------AFRFVQVGIAITNKRCQRPSVFTDVMSHIEFIRRIFLTQNGNDRNQ 278
            |..:        ::.|.|.|:|      .:|:|:|:|..:.::|..:...:..:.:.|
  Fly   369 RQHSRWVAYGVVSYGFTQCGMA------GKPAVYTNVAEYTDWIDSVVQQRKKSQQTQ 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18420	NP_995715.1	Tryp_SPc	42..264	CDD:214473	76/276 (28%)
CG18420	NP_995715.1	Tryp_SPc	43..267	CDD:238113	76/278 (27%)
CG9737	NP_651783.1	CLIP	28..89	CDD:288855
		Tryp_SPc	149..406	CDD:214473	76/276 (28%)
		Tryp_SPc	150..409	CDD:238113	76/278 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010