DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18420 and modSP

DIOPT Version :9

Sequence 1:	NP_995715.1	Gene:	CG18420 / 2768924	FlyBaseID:	FBgn0028866	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster

Alignment Length:	302	Identity:	71/302 - (23%)
Similarity:	115/302 - (38%)	Gaps:	73/302 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 QFLDSECG-TRSPLKLGPRIVNGKVAVRNS-SPWMAFLHTSSNQ----FICGGTLISRRLVLTAA 83
            |..:.:|| ..:|:|   :..:|...:.|: .||...|:...|:    |.|||:|::..||:|||
  Fly   352 QRCEQDCGQLATPIK---QFSSGGYTINNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDLVITAA 413

  Fly    84 HCFIPNTTIV-----------------------------VRLGEYNRKLKGYREEHQVNRTFQHR 119
            ||.....|.:                             |||.|.....||..|.:.
  Fly   414 HCVYDEGTRLPYSYDTFRVIAAKFYRNYGETTPEEKRRDVRLIEIAPGYKGRTENYY-------- 470

  Fly   120 FYDPNTHANDIALLRLVSNVVYKANIRPICIMWDASWKHHIDSIKVLTG--TGWGRTESMHDSSE 182
                    .|:|||.|.........|||||:.: ||:.........:.|  .|| ..|:.|   |
  Fly   471 --------QDLALLTLDEPFELSHVIRPICVTF-ASFAEKESVTDDVQGKFAGW-NIENKH---E 522

  Fly   183 LRTLDISRQPSKMCA--FGSVLSNQFCAGNWNSNL-CIGDTGG------PVGAMVRYRNAFRFVQ 238
            |:.:....:.:.:|.  ...:.:::||......:| |.||:||      |..|...:..|..|:
  Fly   523 LQFVPAVSKSNSVCRRNLRDIQADKFCIFTQGKSLACQGDSGGGFTSELPTNAFSTWNTARHFL- 586

  Fly   239 VGIAITNKRCQRPSVFTDVMSHIEFIRRIFLTQNGNDRNQPT 280
            .|:........:.:....||::|:....:.|  |..:|:..|
  Fly   587 FGVISNAPNADQCAHSLTVMTNIQHFEDMIL--NAMNRSVET 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18420	NP_995715.1	Tryp_SPc	42..264	CDD:214473	62/266 (23%)
CG18420	NP_995715.1	Tryp_SPc	43..267	CDD:238113	62/268 (23%)
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512	1/1 (100%)
		Tryp_SPc	371..616	CDD:214473	62/266 (23%)
		Tryp_SPc	371..591	CDD:304450	59/241 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437297
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030