DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18420 and CG30187

DIOPT Version :9

Sequence 1:	NP_995715.1	Gene:	CG18420 / 2768924	FlyBaseID:	FBgn0028866	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	96/285 - (33%)
Similarity:	143/285 - (50%)	Gaps:	21/285 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LGSTQFLDSECGTRSPLKLGPRIVNGKVAVRNSSPWMAFLHTSSNQFICGGTLISRRLVLTAAHC 85
            :|::.|||..||....||    |..|..|...:|.|||.:|..:: ||||||||.:|.|||||||
  Fly    18 VGASIFLDQICGINIALK----ITGGHNAAFQNSVWMAAVHNRTH-FICGGTLIHKRFVLTAAHC 77

  Fly    86 FIPNTTIVVRLGEYNRKLKGYREEHQVNRTFQHRFYDPN-THANDIALLRLVSNVVYKANIRPIC 149
            .:......|.||.||:.....|::  |.....|..:|.. ::.|||.||:|.|:|::.|.|||||
  Fly    78 IVDQDVQSVSLGAYNKSDPADRKD--VITAVVHSSFDVRASYENDIGLLKLSSDVIFNALIRPIC 140

  Fly   150 IMWDASWKHHIDSIKVLTGTGWGRTESMHDSSELRTLDISRQPSKMC-----AFGSVLSNQFCAG 209
            |:.:.|..:|:.:::.....|||.......|..|:|:.::....:.|     .:.|  ..|.|||
  Fly   141 IVLNKSMANHMRNMRTFKAFGWGTLRGNKTSDILQTIILNHLDREECYMELSVYPS--EKQICAG 203

  Fly   210 NWNSNLCIGDTGGPVGAMVRYRN-AFRFVQVGIAITNK-RCQRPSVFTDVMSHIEFIRRIFLTQN 272
            ..:.:.|.||:|||:...|..:. ..|.||.||....| .|....|:||:||..::|:......:
  Fly   204 VPSGDTCGGDSGGPLTNDVFIQGIGNREVQFGIISVGKTSCDGQGVYTDLMSFADWIKMTIERLS 268

  Fly   273 GNDRNQPTP----KPDKEPEFDWNN 293
            ..|..|..|    .|.::..|.:|:
  Fly   269 IEDEPQSAPFYKIIPQQQDVFLYND 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18420	NP_995715.1	Tryp_SPc	42..264	CDD:214473	81/229 (35%)
CG18420	NP_995715.1	Tryp_SPc	43..267	CDD:238113	82/231 (35%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	82/233 (35%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.960