Protein Alignment CG18420 and F7

DIOPT Version :10

• Sequence 1: NP_995715.1
• Gene: CG18420 / 2768924
• FlyBaseID: FBgn0028866
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: XP_011535776.2
• Gene: F7 / 2155
• HGNCID: 3544
• Length: 495
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 80/282 - (28%)
• Similarity: 130/282 - (46%)
• Gaps: 36/282 - (12%)

  Fly    24 TQFLDSECG------TRSPLKLGPRIVNGKVAVRNSSPWMAFLHTSSNQFICGGTLISRRLVLTA 82
            |..::..||      .|:..|...|||.|||..:...||...|..:..| :||||||:...|::|
Human   217 TPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQ-LCGGTLINTIWVVSA 280

  Fly    83 AHCF--IPN-TTIVVRLGEYN-RKLKGYREEHQVNRTFQHRFYDPNTHANDIALLRLVSNVVYKA 143
            ||||  |.| ..::..|||:: .:..|..:..:|.:......|.|.|..:|||||||...||...
Human   281 AHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTD 345

  Fly   144 NIRPICIMWDASWKHHIDSIKVLTGTGWGR-TESMHDSSELRTLDISRQPSKMCAFGS------- 200
            ::.|:|:......:..:..::....:|||: .:....:.||..|::.|..::.|...|
Human   346 HVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSP 410

  Fly   201 -VLSNQFCAG--NWNSNLCIGDTGGPVGAMVRYRNAFRFVQVGIAITNKRCQRP---SVFTDVMS 259
             :....||||  :.:.:.|.||:|||  ....||..:..  .||....:.|...   .|:|.|..
Human   411 NITEYMFCAGYSDGSKDSCKGDSGGP--HATHYRGTWYL--TGIVSWGQGCATVGHFGVYTRVSQ 471

  Fly   260 HIEFIRRIFLTQNGNDRNQPTP 281
            :||:::::.       |::|.|
Human   472 YIEWLQKLM-------RSEPRP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18420	NP_995715.1	Tryp_SPc	42..264	CDD:214473	72/239 (30%)
F7	XP_011535776.2	GLA	36..97	CDD:214503
		EGF_CA	99..135	CDD:238011
		FXa_inhibition	180..216	CDD:464251
		Tryp_SPc	242..478	CDD:238113	71/240 (30%)