DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and st14b

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_005161261.1	Gene:	st14b / 777629	ZFINID:	ZDB-GENE-061103-613	Length:	864	Species:	Danio rerio

Alignment Length:	288	Identity:	78/288 - (27%)
Similarity:	121/288 - (42%)	Gaps:	47/288 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 CSQFLDPACGIRT---------------QSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGS 74
            |...|:|.|...|               :...:.||:.|..:.....||.|.||..|...|||.|
Zfish   590 CISKLNPMCDGETDCVDGSDEAECKCGKKPHKSSRIVGGKDSDEGEWPWQVSLHMKTQGHVCGAS 654

  Fly    75 LITDKLVLTAAHCFIANQHL--------VARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLY 131
            :|::..::|||||...|...        ...||.:.:..:.:.|        :..|.....|..|
Zfish   655 VISNSWLVTAAHCVQDNDQFRYSQADQWEVYLGLHNQGETSKST--------QRSVLRIIPHPQY 711

  Fly   132 DPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDLLTATGWGKTQMESDS--DALQ 194
            |.:::.||||::.|...|....||.|||:...   .||......:..|||||.:..||:  ..||
Zfish   712 DHSSYDNDIALMELDSPVTLNQNIWPICLPDP---THYFPAGKSVWITGWGKLREGSDAVPSVLQ 773

  Fly   195 TLDIRRQPPDVCAKFIGQTIAGNQFCAG--NWDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASY 257
            ..::|.....||:|.:...|..:..|||  :...:.|.||||||:.::   :...|....|:.|:
Zfish   774 KAEVRIINSTVCSKLMDDGITPHMICAGVLSGGVDACQGDSGGPMSSI---EGNGRMFLAGVVSW 835

  Fly   258 TN----RNCQKASVFTDVLSHAEFILRV 281
            .:    ||  :..|:|.|..:..:|..:
Zfish   836 GDGCGRRN--RPGVYTRVTDYRSWIREI 861

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	72/249 (29%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	71/248 (29%)
st14b	XP_005161261.1	SEA	92..180	CDD:279699
		CUB	233..342	CDD:238001
		CUB	351..457	CDD:238001
		LDLa	465..497	CDD:238060
		LDLa	499..533	CDD:238060
		LDLa	536..570	CDD:238060
		LDLa	578..613	CDD:238060	5/22 (23%)
		Tryp_SPc	624..858	CDD:214473	72/249 (29%)
		Tryp_SPc	625..861	CDD:238113	72/251 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910