DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Prss36

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	347	Identity:	93/347 - (26%)
Similarity:	131/347 - (37%)	Gaps:	89/347 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 QFLDPACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIAN 91
            :|.|..||   :...:.||:.|..|...:.||.|.||.... .:||||||....||:|||||:.|
Mouse    33 EFEDLDCG---RPEPSSRIVGGSDAHPGTWPWQVSLHQGGG-HICGGSLIAPSWVLSAAHCFVTN 93

  Fly    92 ------QHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHAN-----DIAILRL 145
                  ..|...||.:.:....|         ..||....   .:..|:.::.     |:|:|||
Mouse    94 GTLEPADELSVLLGVHSQDGPLE---------GAHMRSVA---TILIPDNYSTVELGADLALLRL 146

  Fly   146 SKSVVYRDNIRPICVVWDHRWRHYLDKIDLLTATGWGKTQ-----------MESD-----SDALQ 194
            :.......::||:|:   .|..|.........|||||..|           .|.:     ..|.|
Mouse   147 ASPAKLGPSVRPVCL---PRASHLFAHGTACWATGWGDVQEAVPLPLPWVLQEVELRLLGEAACQ 208

  Fly   195 TLDIRRQPPDVCAKFI-GQTIAGNQFCAGNWDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASY- 257
            .|..|..|.::..:.: |...||  :.||..|:  |.|||||||    ..::..|:...||.|:
Mouse   209 CLYSRPGPFNLTFQLLPGMLCAG--YPAGRRDT--CQGDSGGPL----VCEDGGRWFLAGITSFG 265

  Fly   258 ---TNRNCQKASVFTDVLSHAEFILR---------------------VWRMYGKGQTLPIPK--K 296
               ..||  :..|||.|..:..:|..                     .|....:..|...|:  |
Mouse   266 FGCGRRN--RPGVFTAVAPYESWIREHVMGSEPGPVFPSQLQKPQSGPWEPREENCTFAQPECGK 328

  Fly   297 PPTTTRPPTW-WHT-TRIPKQT 316
            .|   ||.|| |.. ..:|..|
Mouse   329 AP---RPGTWPWEAQVTVPGST 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	76/265 (29%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	75/264 (28%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	76/267 (28%)
		Tryp_SPc	331..532	CDD:389826	7/17 (41%)
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910