DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and Prss44

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_683742.2	Gene:	Prss44 / 73336	MGIID:	1920586	Length:	372	Species:	Mus musculus

Alignment Length:	288	Identity:	80/288 - (27%)
Similarity:	119/288 - (41%)	Gaps:	70/288 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHLVA 96
            |||.||.     ||:.|..|.....||.|.| ......:||||||:...|:|||||...:.....
Mouse   104 ACGHRTA-----RIVGGRPAPARKWPWQVSL-QVHKQHICGGSLISKWWVITAAHCVYGHLDYAV 162

  Fly    97 RLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDP-------------NTHANDIAILRLSKS 148
            .:|:                     .|...|..:..|             .|..:|||::.|:..
Mouse   163 FMGD---------------------ADLWSKRPVRIPVQDIIVHQDFSMMRTVVHDIALVLLAFP 206

  Fly   149 VVYRDNIRPICVVWDHRWRHYLDKIDLLT-ATGWGKT-QMESDSDALQTLDIRRQPPDVCAKFIG 211
            |.|..||:|:|:    ..:.:|.:...|. .|||||. :....|..||.:::.....:.|.:.:
Mouse   207 VNYSVNIQPVCI----PEKSFLVQPGTLCWVTGWGKVLEQGRSSRILQEIELNIIRHEKCNQIL- 266

  Fly   212 QTIAGNQF--------CAGN-WDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNCQK--- 264
            :.|.||.|        |..| ...:.|.|||||||  |.....|  :|||||.|: ...|.:
Mouse   267 KDIMGNIFTLVQEGGVCGYNEKGGDACQGDSGGPL--VCEFNKT--WVQVGIVSW-GLGCGRIGY 326

  Fly   265 ASVFTDVLSHAEFILR------VWRMYG 286
            ..|:|:|..:.::|::      .|::.|
Mouse   327 PGVYTEVSYYRDWIIKELSRASCWKLSG 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	72/260 (28%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	71/259 (27%)
Prss44	NP_683742.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	31..72
		Tryp_SPc	111..340	CDD:214473	72/260 (28%)
		Tryp_SPc	112..340	CDD:238113	71/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910