DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18636 and c1s

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_002941253.2	Gene:	c1s / 613055	XenbaseID:	XB-GENE-995410	Length:	691	Species:	Xenopus tropicalis

Alignment Length:	278	Identity:	85/278 - (30%)
Similarity:	124/278 - (44%)	Gaps:	62/278 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHC-------- 87
            |.||:. ||..:.||..|..||....|||:   ..||:.:.|||||:|:.||||||.
Frog   424 PVCGVH-QSDKSGRIFGGTRAKPGQFPWMI---QFTDIELGGGSLISDRWVLTAAHVVNKKIFPT 484

  Fly    88 -------FIANQHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHA-------N 138
                   |..|.:|.:   :.:|.::::.                ..|.||..|...       |
Frog   485 MFGGVMKFFPNTNLQS---QEKRLQAKKI----------------IIHPLYQDNEDTEGQSNFDN 530

  Fly   139 DIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKI--DLLTATGWGKTQMESDSDALQTLDIRRQ 201
            |||:::|:|.|.....|.|||:.     |..|..:  ::.|..|||||:....:..||...|...
Frog   531 DIALVQLTKKVKLGSCISPICLP-----RRGLAPVVNEVATIAGWGKTEKRESAVNLQFASISLS 590

  Fly   202 PPDVCAKFIGQT--IAGNQFCAGN---WDSNLCNGDSGGPLGAVITH-KNTQRFVQVGIASYTNR 260
            ..|.|.|..|..  ...|..|||:   .||  |||||||||  :.|. :::.:....||.|:..|
Frog   591 SMDKCKKATGGKGYFTPNMLCAGSDVGKDS--CNGDSGGPL--MFTDPQDSSKMYMAGIVSWGPR 651

  Fly   261 NCQKASVFTDVLSHAEFI 278
            :|....::|.|.::.::|
Frog   652 DCGTYGLYTKVDNYLDWI 669

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	79/263 (30%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	78/262 (30%)
c1s	XP_002941253.2	CUB	21..131	CDD:238001
		FXa_inhibition	145..173	CDD:405372
		CUB	177..288	CDD:238001
		PHA02927	301..>436	CDD:222943	5/12 (42%)
		Tryp_SPc	436..669	CDD:214473	79/263 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910