DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and tmprss9

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_021325244.1	Gene:	tmprss9 / 562051	ZFINID:	ZDB-GENE-050208-573	Length:	788	Species:	Danio rerio

Alignment Length:	290	Identity:	75/290 - (25%)
Similarity:	115/290 - (39%)	Gaps:	47/290 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCF-IAN--QHL 94
            |...|:...:.||:.|...::...||.|.|. ......||.|::..:.:::||||| :.|  :..
Zfish   220 CSCGTRPVMSNRIVGGENTRHGEFPWQVSLR-LRGRHTCGASIVNSRWLVSAAHCFEVENNPKDW 283

  Fly    95 VARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPIC 159
            .|.:|. .:....|...:..|.:...|      ...|||.|..:|:.:|.|...:.:...::|:|
Zfish   284 TALVGA-NQVSGAEAEAFIVNIKSLVM------SPKYDPMTTDSDVTVLELETPLKFSHYVQPVC 341

  Fly   160 VVWDHRWRHYLDKIDLLTATGWG-----KTQMESDSDALQTLDIRRQPPDVCAK---FIGQTIAG 216
            :...   .|..........:|||     .|::.|   .||...::.....||.|   :.| .:..
Zfish   342 IPSS---SHVFTPGQNCIVSGWGALNQYTTEVPS---TLQKAIVKIIDSKVCNKSSVYRG-ALTQ 399

  Fly   217 NQFCAGNWDSNL--CNGDSGGPLGAVITHKNTQRFVQVGIASYTNRNC---QKASVFTDVLSHAE 276
            |..|||.....:  |.|||||||...:.   ..|:...||.|: ...|   .|..|::.|..
Zfish   400 NMMCAGFLQGKVDSCQGDSGGPLACEVA---AGRYFLAGIVSW-GVGCAQINKPGVYSRVTK--- 457

  Fly   277 FILRVWRM-YGKGQTLPI----PKKPPTTT 301
              ||.|.: |.|  |.|.    |..|..||
Zfish   458 --LRNWIVSYTK--TAPAFQENPTVPSVTT 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	62/249 (25%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	61/248 (25%)
tmprss9	XP_021325244.1	SEA	52..146	CDD:307516
		LDLa	185..220	CDD:238060	75/290 (26%)
		Tryp_SPc	232..462	CDD:238113	63/253 (25%)
		LDLa	510..544	CDD:238060
		Tryp_SPc	557..783	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910