DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and f2

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001015797.1	Gene:	f2 / 548514	XenbaseID:	XB-GENE-481539	Length:	607	Species:	Xenopus tropicalis

Alignment Length:	298	Identity:	79/298 - (26%)
Similarity:	129/298 - (43%)	Gaps:	65/298 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DPACGIR----------------TQSRTAYRIINGHTAKYNSSPWMVFLHSTTDM-FVCGGSLIT 77
            :..||:|                .:|....||:.|.||:..|:||.|.|...:.. .:||.||::
Frog   319 EAVCGLRPLFEQKSVEDKGEKELLESYMQGRIVKGETAEPGSAPWQVMLFKKSPQELLCGASLLS 383

  Fly    78 DKLVLTAAHCFI--------ANQHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPN 134
            |:.||:||||..        ....::.|:|::.||:.|..|......  |.::    .|..|:..
Frog   384 DRWVLSAAHCIFYPPWDKNYTTDDILVRIGKHFRTKYERATERIAQL--ERII----VHPKYNWK 442

  Fly   135 THAN-DIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDLLTA------TGWGKTQ------M 186
            .:.: |||:::|.:.|.:.:.|.|:|:....      ..:.||.|      ||||..|      .
Frog   443 ENLDRDIALIQLKRPVAFSNYIHPVCLPTKD------TVVKLLAAGYKGRVTGWGNLQETWTSGA 501

  Fly   187 ESDSDALQTLDIRRQPPDVCAKFIGQTIAGNQFCAG-----NWDSNLCNGDSGGPLGAVITHKNT 246
            ::...|||.:::.....:.|.......:..|.||||     :...:.|.||||||.  |:...:|
Frog   502 QNLPQALQQINLPIVDQETCKSSTNIKVTDNMFCAGYNPEDSKRGDACEGDSGGPF--VMKDPDT 564

  Fly   247 QRFVQVGIASYTNRNCQKASVFTDVLSHAEFILRVWRM 284
            .|:||:||.|: ...|.:.:.:       .|.:.|.||
Frog   565 GRWVQLGIVSW-GEGCDRDNKY-------GFYVHVHRM 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	71/260 (27%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	70/259 (27%)
f2	NP_001015797.1	GLA	23..86	CDD:214503
		KR	106..185	CDD:214527
		KR	206..287	CDD:214527
		Thrombin_light	303..349	CDD:370463	4/29 (14%)
		Tryp_SPc	349..598	CDD:214473	75/268 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910