DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and prss60.2

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	265	Identity:	86/265 - (32%)
Similarity:	117/265 - (44%)	Gaps:	44/265 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTT-DMFVCGGSLITDKLVLTAAHCF--IANQHL 94
            ||   |:....||:.|..|...|.||.|.|.|.. ....||||||:.:.|||||||.  ::...|
Zfish    25 CG---QAPLNSRIVGGVNAPEGSWPWQVSLQSPRYGGHFCGGSLISSEWVLTAAHCLPGVSESSL 86

  Fly    95 VARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPIC 159
            |..||.    |:::....:...|....:   ..|..|:.||:.||||:||||.:|.:.|.|||:|
Zfish    87 VVYLGR----RTQQGVNTHETSRNVAKI---IVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVC 144

  Fly   160 VVWDH--------RWRHYLDKIDLLTATGWGKTQMESDSDA---LQTLDIRRQPPDVCAKFIGQ- 212
            :...:        .|           .||||..|...:..|   ||...|.....|.|...:|.
Zfish   145 LAAQNSVYSAGTSSW-----------ITGWGDVQAGVNLPAPGILQETMIPVVANDRCNAQLGSG 198

  Fly   213 TIAGNQFCAG--NWDSNLCNGDSGGPLGAVITHKNTQRFVQVGIAS--YTNRNCQKASVFTDVLS 273
            |:..|..|||  ....:.|.||||||:   :|...|. ::|.||.|  |...:.....|:|.|..
Zfish   199 TVTNNMICAGLAKGGKDTCQGDSGGPM---VTRLCTV-WIQAGITSWGYGCADPNSPGVYTRVSQ 259

  Fly   274 HAEFI 278
            :..:|
Zfish   260 YQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	82/252 (33%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	81/251 (32%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	82/252 (33%)
		Tryp_SPc	34..267	CDD:238113	82/253 (32%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910