DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and proz

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001116189.1	Gene:	proz / 496781	XenbaseID:	XB-GENE-971425	Length:	416	Species:	Xenopus tropicalis

Alignment Length:	304	Identity:	62/304 - (20%)
Similarity:	110/304 - (36%)	Gaps:	100/304 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LHSGCSQFLDP------------------------------ACGIRTQSRTAYRIINGHTA---- 51
            :..||..|..|                              |||         :|:|...:
Frog   133 MEDGCQHFCHPSYEADSYSCSCANGYKLGADEKSCHPEDPFACG---------QILNLEVSITKN 188

  Fly    52 ----KYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCF--------IANQHLVARLGEYERT 104
                :.:..||.|.:.::..:.||.|.::::.:|||.|.|.        :|.....:.||:.:..
Frog   189 RNHLQADIFPWQVPVLNSQKVQVCSGVVLSESVVLTTASCITMYDPYFVVAGVQQKSGLGQRQMI 253

  Fly   105 RSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHY 169
            |.:.        ::.||        .|...|..|:||:|:|.:.:|:.:|..|||:.......:.
Frog   254 RVKT--------KQVHM--------RYSEETGDNNIALLKLKEKIVFHNNSLPICIPQKDFAENV 302

  Fly   170 LDKIDLLTATGWGKTQMESDSDALQTLDIRRQ---PPDVCAKFIGQTIAGNQFCAGNW---DSNL 228
            |...:....:|| |:..|.::|||..:....:   ..:||.:.:..|.....||..:.   ||.|
Frog   303 LVPFNTGLVSGW-KSSSEEEADALIPIQFYTKYTNRTEVCEQSLNVTQTNRMFCGVSHEAIDSEL 366

  Fly   229 CNGDS-----------GGPLGA---VITHKNTQRFVQVGIASYT 258
            ..|..           ||.:|:   .:.:|        |:.|:|
Frog   367 SEGGHLAVQHNGVWFLGGIMGSWQPTLLNK--------GVFSFT 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	55/251 (22%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	55/250 (22%)
proz	NP_001116189.1	GLA	22..85	CDD:214503
		EGF_CA	92..123	CDD:238011
		FXa_inhibition	136..167	CDD:373209	4/30 (13%)
		Tryp_SPc	197..414	CDD:389826	53/231 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910