DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP012504

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_001231011.2	Gene:	AgaP_AGAP012504 / 4578496	VectorBaseID:	AGAP012504	Length:	839	Species:	Anopheles gambiae

Alignment Length:	285	Identity:	76/285 - (26%)
Similarity:	128/285 - (44%)	Gaps:	58/285 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PACGIRTQSRT-AYRIINGHTAKYNSSPWMVFLHSTTDMFVCGGSLITDKLVLTAAHCFIANQHL 94
            ||.|.....|. |:....|.|.:..|..|:           ||||||.:..:||||||...:.::
Mosquito    19 PAAGSPAYLREFAHIAAIGWTNEDQSVRWL-----------CGGSLIWENFILTAAHCAADDDNV 72

  Fly    95 ---VARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIR 156
               |||:|:......|:     ..|.::..:....:|..:..|::..|||:::|.::|...|.:.
Mosquito    73 PPDVARMGDINIYSDED-----DEFAQQLKIVEIIRHPKHKYNSNYYDIALMKLERNVTLHDTVA 132

  Fly   157 PICVVWDHRWRHYLDKIDL--LTATGWGKTQMESDSDALQT-LDIRRQP--PDVCA-------KF 209
            |.|:..|       |:|..  |.|.|||:|..  |.:..:| |.::..|  .|.|:       :.
Mosquito   133 PSCLWLD-------DEIRFPELLAAGWGRTGF--DQNTTKTLLKVQLAPITNDKCSTHYQRGVRK 188

  Fly   210 IGQTIAGNQFCAGNWDSNLCNGDSGGPLGAVITHKNTQRFVQ-------VGIASYTNRNCQKAS- 266
            :...:..:|||||:...:.|.|||||||       :.:.|.:       ||:.|: .:.|..|:
Mosquito   189 LENGLMDHQFCAGDEKMDTCPGDSGGPL-------HVKLFKEWKLIPFLVGVTSF-GKACGLAAP 245

  Fly   267 -VFTDVLSHAEFILRVWRMYGKGQT 290
             |:..|....::|:...:.:|:..|
Mosquito   246 GVYVKVSKFGDWIIETLQRHGEMAT 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	68/257 (26%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	68/256 (27%)
AgaP_AGAP012504	XP_001231011.2	Tryp_SPc	22..261	CDD:238113	72/271 (27%)
		Tryp_SPc	22..258	CDD:214473	71/268 (26%)
		Trypsin	327..528	CDD:278516
		Tryp_SPc	333..>433	CDD:304450
		Tryp_SPc	611..836	CDD:304450
		Tryp_SPc	611..832	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910