DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP012502

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_001230484.2	Gene:	AgaP_AGAP012502 / 4578454	VectorBaseID:	AGAP012502	Length:	829	Species:	Anopheles gambiae

Alignment Length:	237	Identity:	60/237 - (25%)
Similarity:	99/237 - (41%)	Gaps:	32/237 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 CGGSLITDKLVLTAAHCFIANQHL----VARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLY 131
            ||||||....:||||||......|    :.|:|:.......|..     ..:|..:....:|.||
Mosquito    46 CGGSLIWANFILTAAHCTKDRDTLLPPDIIRIGDLNLYDDREDA-----LVQERTIIRVIRHPLY 105

  Fly   132 DPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDL--LTATGWGKTQM-ESDSDAL 193
            :.::...|||:|.|::.|.....:.|.|:..|       |.|..  :.|.|||.:.. ...::.|
Mosquito   106 NTSSVFYDIALLMLNEKVNIYFEVMPTCLWLD-------DNIPFSKVEAAGWGTSGFGYGKTNIL 163

  Fly   194 QTLDIRRQPPDVCAKFIGQT------IAGNQFCAGNWDS--NLCNGDSGGPLGAVITHKNTQRFV 250
            ...:::......|..:..|.      :..:|.||  ||.  :.|.|||||||...:...:.:...
Mosquito   164 IKAELKLMANKDCESYYSQVASVKNGLMEHQLCA--WDKVMDTCPGDSGGPLQHKLIFGDYKVPF 226

  Fly   251 QVGIASYTNRNC--QKASVFTDVLSHAEFILRVWRMYGKGQT 290
            .||:.|: ..:|  .:..|:..|.....:|:...:.:|:..|
Mosquito   227 LVGVTSF-GLSCGNSQPGVYVKVSKFGSWIVETLQQHGERVT 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	57/223 (26%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	57/223 (26%)
AgaP_AGAP012502	XP_001230484.2	Tryp_SPc	19..258	CDD:238113	58/226 (26%)
		Tryp_SPc	19..255	CDD:214473	57/223 (26%)
		Tryp_SPc	325..>418	CDD:304450
		Trypsin	621..823	CDD:278516
		Tryp_SPc	629..826	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910