DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP000411

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_001237291.3	Gene:	AgaP_AGAP000411 / 4576124	VectorBaseID:	AGAP000411	Length:	1091	Species:	Anopheles gambiae

Alignment Length:	289	Identity:	73/289 - (25%)
Similarity:	128/289 - (44%)	Gaps:	50/289 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDM---FVCGGSLITDKLVLTAAHC------ 87
            :|| |.:.:|.|.|.||..|.....||...:....|.   :.||||::.:..:|||:||
Mosquito    11 SCG-RRKVKTTYLIHNGADAIAGHWPWHAAIFHQKDKHKEYACGGSILDETTILTASHCVSTLSG 74

  Fly    88 FIANQHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYR 152
            .|:...:...:|:....:|.|.|..:  ...|.:::.||...     :..:|||:::|..::...
Mosquito    75 VISAALVTVHVGQIHLNQSSEYTQTF--EAREIIINPGFSKA-----SIIHDIALIKLRTNISMN 132

  Fly   153 DNIRPICVVWDHRWRHYLDK-IDLL-----TATGWGKTQMESDSDALQTLDIRRQPPDVCAK--- 208
            ..::|:|:     |.  :|. ::|:     |..|:|.::.:..|:.|:...|....|..|..
Mosquito   133 RYVQPVCL-----WT--MDSALELIVGRNGTIVGFGLSERDVVSEQLKQATIGVVDPYTCIASDR 190

  Fly   209 -FIGQTIAGNQFCA-GNWDSNLCNGDSGGPLGAVITHKNTQRFVQVGIASYTNRN-----CQ--K 264
             ..|..:....||. |....:.||||||   |.:....:.:.||: |:.|:|...     |.  |
Mosquito   191 VVYGTHLTLEMFCGKGQNGVSACNGDSG---GGMFFEVSGRWFVR-GLVSFTPARGSSGLCDPLK 251

  Fly   265 ASVFTDVLSHAEFILRVWRMYGKGQTLPI 293
            .:|:|||..:.|:|    :.|...:.||:
Mosquito   252 YTVYTDVAKYVEWI----KQYIDQRVLPV 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	64/260 (25%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	64/259 (25%)
AgaP_AGAP000411	XP_001237291.3	Tryp_SPc	23..267	CDD:238113	65/265 (25%)
		Tryp_SPc	25..265	CDD:214473	63/257 (25%)
		Tryp_SPc	308..>462	CDD:304450
		Trypsin	838..1069	CDD:278516
		Tryp_SPc	864..>946	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910