DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and AgaP_AGAP012777

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_001230468.2	Gene:	AgaP_AGAP012777 / 4397664	VectorBaseID:	AGAP012777	Length:	465	Species:	Anopheles gambiae

Alignment Length:	183	Identity:	52/183 - (28%)
Similarity:	82/183 - (44%)	Gaps:	33/183 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 FREEHMVDAGFKHKLYDPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDLL---- 176
            |.:||.|.....|..|:.:...||||:::|::|:...:.::|:|:     |.  :||...|
Mosquito     7 FVQEHTVQELIVHPGYNSSRFVNDIALIKLTESITMSEFVQPVCL-----WT--MDKNQELIVGK 64

  Fly   177 --TATGWGKTQMESDSDALQTLDIRRQPPDVCAK-----FIGQTIAGNQFCAGNWDSNL--CNGD 232
              |..|:|..:.:..|:.|:...|.......|.|     |..| :....||.|. .||:  ||||
Mosquito    65 TGTLVGFGLNEQDVVSEQLKQASIGVVDALTCIKSDRLSFANQ-LTAEMFCGGG-QSNVSACNGD 127

  Fly   233 SGGPLGAVITHKNTQRFVQVGIASY---TNRN--C--QKASVFTDVLSHAEFI 278
            |||.|...:..|   .||: |:.|:   ..|.  |  .|.:.:.||..:..:|
Mosquito   128 SGGGLFFNVEGK---WFVR-GVVSFIPVRQRTGLCDPSKYTAYADVAKYLGWI 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	51/181 (28%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	51/181 (28%)
AgaP_AGAP012777	XP_001230468.2	Tryp_SPc	<1..178	CDD:238113	52/183 (28%)
		Tryp_SPc	<4..176	CDD:214473	51/181 (28%)
		Tryp_SPc	219..458	CDD:214473
		Tryp_SPc	219..458	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910