DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18636 and modSP

DIOPT Version :9

Sequence 1:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	79/294 - (26%)
Similarity:	117/294 - (39%)	Gaps:	61/294 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 QLLHSGCSQFLDPACGIRTQSRTAYRIINGHTAKYNSSPWMVFL---HSTTDM-FVCGGSLITDK 79
            |.....|.|...|   |:..|...|.|.|      ...||.|.|   |:..|. |.|||||:|..
  Fly   352 QRCEQDCGQLATP---IKQFSSGGYTINN------TVVPWHVGLYVWHNEKDYHFQCGGSLLTPD 407

  Fly    80 LVLTAAHC-----------FIANQHLVARL-GEYERTRSEECTGYYCNFREEHMVD--AGFKHKL 130
            ||:|||||           :...:.:.|:. ..|..|..||      ..|:..:::  .|:|.:
  Fly   408 LVITAAHCVYDEGTRLPYSYDTFRVIAAKFYRNYGETTPEE------KRRDVRLIEIAPGYKGR- 465

  Fly   131 YDPNTHANDIAILRLSKSVVYRDNIRPICVVWDHRWRHYLDKIDLL-----TATGWGKTQMESDS 190
              ...:..|:|:|.|.:.......||||||.    :..:.:|..:.     ...||   .:|:..
  Fly   466 --TENYYQDLALLTLDEPFELSHVIRPICVT----FASFAEKESVTDDVQGKFAGW---NIENKH 521

  Fly   191 DALQTLDIRRQPPDVCAKFIGQTIAGNQFCAGNWDSNL-CNGDSGG------PLGAVITHKNTQR 248
            : ||.:....:...||.:.: :.|..::||......:| |.|||||      |..|..|. ||.|
  Fly   522 E-LQFVPAVSKSNSVCRRNL-RDIQADKFCIFTQGKSLACQGDSGGGFTSELPTNAFSTW-NTAR 583

  Fly   249 FVQVGIASYTNRNCQKA---SVFTDVLSHAEFIL 279
            ....|:.|......|.|   :|.|::....:.||
  Fly   584 HFLFGVISNAPNADQCAHSLTVMTNIQHFEDMIL 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	70/266 (26%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	70/265 (26%)
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512	1/1 (100%)
		Tryp_SPc	371..616	CDD:214473	71/269 (26%)
		Tryp_SPc	371..591	CDD:304450	66/244 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437285
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940